外科理论与实践2026，Vol.31Issue(3)：212-217,6.DOI:10.16139/j.1007-9610.2026.03.06
循环肿瘤DNA在乳腺癌精准诊疗中的应用与展望
Application and prospects of circulating tumor DNA in the precision diagnosis and treatment of breast cancer
摘要
Abstract
Circulating tumor DNA(ctDNA)represents the liquid biopsy technology with the most advanced clinical translation and the deepest research foundation to date.Leveraging its non-invasive,dynamic,and highly specific advantages,ctDNA has emerged as an important breakthrough direction in the precision diagnosis and treatment of breast cancer.In this article,we systematically reviewed the detection methodologies of ctDNA,with a dedicated focus on its clinical utility and current research status across different stages of breast cancer management.Furthermore,we provided a forward-looking perspective on the future development of ctDNA in guiding the full-course precision management of breast cancer.关键词
乳腺癌/循环肿瘤DNA/精准医疗/预后预测/疗效评估Key words
Breast cancer/Circulating tumor DNA(ctDNA)/Precision medicine/Prognostic prediction/Efficacy evaluation分类
医药卫生引用本文复制引用
王豪雨,朱思吉,李安琪,陈小松..循环肿瘤DNA在乳腺癌精准诊疗中的应用与展望[J].外科理论与实践,2026,31(3):212-217,6.基金项目
国家自然科学基金(82403868,82573726) （82403868,82573726）
上海市卫生健康委员会智慧医疗专项研究项目(2025ZHYL003). （2025ZHYL003）
