临床医学工程2026，Vol.33Issue(7)：790-794,5.DOI:10.3969/j.issn.1674-4659.2026.07.0790
乌梅丸加减联合温针灸治疗子宫内膜异位症伴痛经的临床效果研究
Study on the Clinical Effect of Modified Wumei Pill Combined with Warm Acupuncture and Moxibustion in the Treatment of Endometriosis Complicated with Dysmenorrhea
摘要
Abstract
Objective To investigate the clinical effect of modified Wumei Pill combined with warm acupuncture and moxibustion in the treatment of patients with endometriosis(EMT)complicated with dysmenorrhea.Methods A total of 124 patients diagnosed with EMT complicated with dysmenorrhea in our hospital from August 2023 to August 2025 were selected and divided into the control group and the study group by the random number table method,with 62 cases in each group.The control group was treated with oral Drospirenone and Ethinylestradiol Tablets alone,while the study group was treated with modified Wumei Pill combined with warm acupuncture and moxibustion on this basis.The clinical efficacy,pain and symptom scores,levels of biochemical indicators[serum carbohydrate antigen 125(CA125),prostaglandin E2(PGE2),prostaglandin F2α(PGF2α),tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)]and the occurrence of adverse reactions were compared between the two groups.Results There was a significant difference in the distribution of clinical efficacy grades between the two groups(Z=-2.987,P=0.003).The total effective rate of the study group was 91.94％,significantly higher than 77.42％of the control group(P＜0.05).After treatment,the Visual Analogue Scale(VAS)score,Cox Menstrual Symptom Scale(CMSS)score and the levels of serum CA125,PGE2,PGF2α,TNF-α and IL-6 in the study group were significantly lower than those in the control group(P＜0.05).The total incidence of adverse reactions in the study group was lower than that in the control group(3.23％vs.12.90％,P＜0.05).Conclusions On the basis of oral Drospirenone and Ethinylestradiol Tablets,modified Wumei Pill combined with warm acupuncture and moxibustion can further improve the clinical efficacy of patients with EMT complicated with dysmenorrhea,effectively relieve dysmenorrhea symptoms,reduce the levels of serum pain-causing prostaglandins,pro-inflammatory factors and CA125,and reduce western medicine-related adverse reactions,which has high clinical promotion value.关键词
子宫内膜异位症/痛经/乌梅丸/温针灸/促炎因子/糖类抗原125Key words
Endometriosis/Dysmenorrhea/Wumei Pill/Warm acupuncture and moxibustion/Pro-inflammatory factor/Carbohy drate antigen 125分类
医药卫生引用本文复制引用
周倩羽,曾逸兴,吴志机,李茂清,董平儒..乌梅丸加减联合温针灸治疗子宫内膜异位症伴痛经的临床效果研究[J].临床医学工程,2026,33(7):790-794,5.基金项目
茂名市科技专项资金项目(编号:茂科字[2023]83号-28) （编号:茂科字[2023]83号-28）
