中国畜牧杂志2026，Vol.62Issue(8)：25-34,10.DOI:10.19556/j.0258-7033.20250527-08
猪早期胚胎发育节点、谱系分化机制及发育不均的影响因素
Early Pig Embryonic Development:Key Stages,Lineage Differentiation Mechanisms,and Determinants of Developmental Asynchrony
摘要
Abstract
As both a vital livestock species and a biomedical model organism,pig serve as a critical system for studying early embryonic development.Understanding this process is significant implications for advancing livestock breeding strategies and developing models for human diseases.However,the signaling pathways,molecular interactions,and regulatory mechanisms—including metabolic regulation—underlying porcine early embryogenesis remain incompletely characterized.This review systematically summarizes key developmental events across successive stages of porcine early embryogenesis,encompassing lineage specification dynamics and associated signaling pathway alterations.Furthermore,we critically examine potential factors contributing to developmental asynchrony in pig embryos,offering mechanistic insights that may enhance mammalian reproductive efficiency and inform human reproductive health research.关键词
猪/早期胚胎发育/谱系分化/发育异质性Key words
Pig/Early embryonic development/Lineage differentiation/Developmental heterogeneity分类
农业科技引用本文复制引用
李思雨,孟岳阳,王毓甜,周财源,曾祥芳..猪早期胚胎发育节点、谱系分化机制及发育不均的影响因素[J].中国畜牧杂志,2026,62(8):25-34,10.基金项目
国家自然科学基金项目(32425052) （32425052）
北京市卓越青年科学家计划 （）
