转化医学杂志2026，Vol.15Issue(8)：1313-1319,7.DOI:10.3639/j.issn.2095-3097.2026.08.010
肠系膜上动脉超声联合AGIUS对危重患者急性胃肠损伤及预后的评估价值
Predictive Value of Superior Mesenteric Artery Ultrasonography Combined with Acute Gastrointestinal Injury Ultrasound Score for Acute Gastrointestinal Injury and Prognosis in Critically Ill Patients
摘要
Abstract
Objective To investigate the value of superior mesenteric artery peak systolic velocity(SMAPSV)combined with acute gastrointestinal injury ultrasound score(AGIUS)in predicting acute gastrointestinal injury(AGI)occurrence and 28-day prognosis in critically ill patients.Methods A total of 125 serious patients admitted to the Department of Critical Care Medicine,Nanjing First Hospital,from May to October 2025 were prospectively enrolled.The AGI grade and 28-day mortality were dynamically monitored.According to the occurrence of AGI,the patients were divided into the AGI group(n=64)and the nonAGI group(n=61).Meanwhile,bedside ultrasound was performed to measure SMAPSV and AGIUS,and a combined scoring system was further established.Spearman correlation analysis was used to analyze the correlation of SMAPSV combined with AGIUS with AGI grade.Multivariate logistic regression analysis was adopted to explore the influencing factors for the risk of AGI in ICU patients.ROC curve was used to evaluate the predictive value of SMAPSV combined with AGIUS for the occurrence of AGI and 28-day mortality in ICU patients.Results Of the 125 patients,the incidence of AGI was 51.20％,and the 28-day mortality rate was 20.00％.ROC curve analysis showed that the AUC of SMAPSV for predicting AGI in ICU patients was 0.736,while the AUC of AGIUS was 0.832.The combined prediction of SMAPSV and AGIUS yielded an AUC of 0.892,which was significantly higher than that of SMAPSV or AGIUS alone(P<0.001).Multivariate Logistic regression analysis demonstrated that the combined index of SMAPSV and AGIUS was an independent influencing factor for the occurrence of AGI in ICU patients(OR=5.291,95％CI:3.656-7.658,P<0.001).Spearman correlation analysis showed that the combination of SMA-PSV and AGIUS was positively correlated with AGI grade,and the index level increased with the elevation of AGI grade(r=0.753,P<0.001).ROC curve analysis also indicated that the AUC of SMAPSV for predicting 28-day mortality in ICU patients was 0.787,and the AUC of AGIUS was 0.811.The combined AUC of SMAPSV and AGIUS was 0.872,which was higher than the individual prediction of SMAPSV and AGIUS(P<0.05),and also higher than the prediction value of the Sequential Organ Failure Assessment score(P<0.001).Conclusion SMAPSV combined with AGIUS is closely correlated with the severity of AGI,and can effectively predict the occurrence of AGI and the shortterm prognosis of critically ill patients.关键词
急性胃肠损伤/肠系膜上动脉/床旁超声/喂养不耐受/预后Key words
acute gastrointestinal injury/superior mesenteric artery/bedside ultrasound/feeding intolerance/prognosis引用本文复制引用
叶梓语,孙加奎,朱旋旋,尹翔,李邵,袁蛟龙,王璐,王翔..肠系膜上动脉超声联合AGIUS对危重患者急性胃肠损伤及预后的评估价值[J].转化医学杂志,2026,15(8):1313-1319,7.基金项目
江苏省自然科学基金面上项目(BK20231128) （BK20231128）
