中医眼耳鼻喉杂志2026，Vol.16Issue(3)：156-160,5.DOI:10.3969/j.issn.1674-9006.2026.03.006
不同倾斜体位下脉络膜血液循环变化的差异研究
Comparative analysis of choroidal circulation changes in varied tilted postures
摘要
Abstract
Objective To investigate the differences in choroidal blood circulation under various tilted positions and analyze the effect of postural changes on subfoveal choroidal thickness(SFCT)and choroidal vascularity index(CVI).Methods Twenty-one healthy subjects(39 eyes)were recruited.Using swept-source optical coherence tomography angi-ography(SS-OCTA),SFCT and CVI were measured at the following time points:baseline sitting position,15° head-up tilt,supine position,15° head-down tilt,and after returning to the baseline position.Repeated-measures analysis of vari-ance(ANOVA)was used to compare parameter changes across different positions and time points.Results Postural changes significantly affected SFCT and CVI.At 15° head-down tilt,SFCT and CVI increased by 15.5％and 16.8％,re-spectively,within 1 minute,peaking at 10 minutes(20.0％increase in SFCT and 19.4％increase in CVI).All parame-ters returned to the baseline level 30 minutes after returning to the baseline position(P＞0.05).ANOVA showed signifi-cant effects for position,time,and their interaction(P＜0.001).Conclusion Postural changes reversibly alter choroidal hemodynamics.The head-down position significantly increases SFCT and CVI,which may be related to gravity-induced venous pressure changes and vascular autoregulation.关键词
脉络膜血液循环/脉络膜厚度/脉络膜血流指数/不同倾斜体位/差异Key words
Choroidal blood circulation/Subfoveal choroidal thickness/Choroidal vascularity index/Different tilted positions/Difference分类
医药卫生引用本文复制引用
陈小凤,黄楷,董睿,潘学会..不同倾斜体位下脉络膜血液循环变化的差异研究[J].中医眼耳鼻喉杂志,2026,16(3):156-160,5.基金项目
四川省科学技术厅-四川省自然科学基金(2023NSFSC1662) （2023NSFSC1662）
