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Sal B-based nanoparticles suppress hepatocellular carcinoma by coordinated modulation of the PI3K-AKT-mTOR axis and direct targeting of LC3B

Xiao-Ke Li Hao-Ran Dang Gong-Hao Xu Jun-Ya Song Sheng-Tao Hu Yan Liu Jun Kang

Traditional Medicine Research2026,Vol.11Issue(12):P.18-29,12.
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Traditional Medicine Research2026,Vol.11Issue(12):P.18-29,12.DOI:10.53388/TMR20251230001

Sal B-based nanoparticles suppress hepatocellular carcinoma by coordinated modulation of the PI3K-AKT-mTOR axis and direct targeting of LC3B

Xiao-Ke Li 1Hao-Ran Dang 1Gong-Hao Xu 1Jun-Ya Song 1Sheng-Tao Hu 1Yan Liu 1Jun Kang1

作者信息

  • 1. School of Life Sciences,Tianjin University,Tianjin 300072,China
  • 折叠

摘要

关键词

Salvianolic acid B/hepatocellular carcinoma/autophagy/LC3B/PI3K-AKT-mTOR pathway/network pharmacology/proteomics/nanoparticles

分类

医药卫生

引用本文复制引用

Xiao-Ke Li,Hao-Ran Dang,Gong-Hao Xu,Jun-Ya Song,Sheng-Tao Hu,Yan Liu,Jun Kang..Sal B-based nanoparticles suppress hepatocellular carcinoma by coordinated modulation of the PI3K-AKT-mTOR axis and direct targeting of LC3B[J].Traditional Medicine Research,2026,11(12):P.18-29,12.

基金项目

supported by Tianjin Key Medical Discipline Construction Project(Grant No.TJYXZDXK-3-020c). (Grant No.TJYXZDXK-3-020c)

Traditional Medicine Research

2413-3973

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