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Early diabetes-like phenotypes in germ-free mice induced by gut microbiota from patients with type 2 diabetes

Jianghao Feng Xing Liu Hua Zhu Yun Yang Wei Liu Xiaoliang Jiang Zhiwei Yang

Animal Models and Experimental Medicine2026,Vol.9Issue(6):P.1202-1216,15.
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Animal Models and Experimental Medicine2026,Vol.9Issue(6):P.1202-1216,15.DOI:10.1002/ame2.70229

Early diabetes-like phenotypes in germ-free mice induced by gut microbiota from patients with type 2 diabetes

Jianghao Feng 1Xing Liu 2Hua Zhu 2Yun Yang 3Wei Liu 4Xiaoliang Jiang 2Zhiwei Yang1

作者信息

  • 1. Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,P.R.China China-Japan Friendship Hospital(Institute of Clinical Medical Sciences),Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,P.R.China
  • 2. Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,P.R.China
  • 3. Taihe County People''s Hospital,The Taihe Hospital of Wannan Medical College,Fuyang,Anhui Province,P.R.China
  • 4. Department of Cardiology,The First Affiliated Hospital of Hebei North University,Zhangjiakou,Hebei Province,P.R.China
  • 折叠

摘要

关键词

germ-free mice/metabolomics/microbiomics/microbiota transplantation/type 2 diabetes

分类

医药卫生

引用本文复制引用

Jianghao Feng,Xing Liu,Hua Zhu,Yun Yang,Wei Liu,Xiaoliang Jiang,Zhiwei Yang..Early diabetes-like phenotypes in germ-free mice induced by gut microbiota from patients with type 2 diabetes[J].Animal Models and Experimental Medicine,2026,9(6):P.1202-1216,15.

基金项目

National Key Research and Development Program of China,Grant/Award Number:2022YFF0710600 ()

Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences,Grant/Award Number:2021-1-I2M-035 ()

Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences,Grant/Award Number:2023-PT180-01 ()

National High-level Innovation and Entrepreneurship Talents Program for Young Backbone Talents(SpringBuds Project),Grant/Award Number:20250333。 (SpringBuds Project)

Animal Models and Experimental Medicine

2096-5451

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