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Kdf1 missense mutation caused enamel defects by disrupting cell adhesion and Hippo-YAP signaling in dental epithelium

Pei Li Runling Zeng Jingyan Xue Yaling Song Jie Wu Binghui Zeng Ling Lin Dongsheng Yu Wei Zhao

International Journal of Oral Science2026，Vol.18Issue(3)：P.561-572,12.

International Journal of Oral Science2026，Vol.18Issue(3)：P.561-572,12.DOI:10.1038/s41368-026-00445-4

Kdf1 missense mutation caused enamel defects by disrupting cell adhesion and Hippo-YAP signaling in dental epithelium

Pei Li ¹Runling Zeng ¹Jingyan Xue ¹Yaling Song ²Jie Wu ¹Binghui Zeng ¹Ling Lin ¹Dongsheng Yu ¹Wei Zhao¹

作者信息

1. Guanghua School of Stomatology,Hospital of Stomatology,Guangdong Provincial Key Laboratory of Stomatology,Sun Yat-Sen University,Guangzhou,China
2. State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine Ministry of Education,Hubei Key Laboratory of Stomatology,School&Hospital of Stomatology,Wuhan University,Wu Han,China
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摘要

关键词

epithelial cellsthe/intracellular regulator/dental epithelium dysfunctionalthough/enamel defect/keratinocyte differentiation factor/amelogenesis imperfecta/KDF mutation

分类

医药卫生

引用本文复制引用

Pei Li,Runling Zeng,Jingyan Xue,Yaling Song,Jie Wu,Binghui Zeng,Ling Lin,Dongsheng Yu,Wei Zhao..Kdf1 missense mutation caused enamel defects by disrupting cell adhesion and Hippo-YAP signaling in dental epithelium[J].International Journal of Oral Science,2026,18(3):P.561-572,12.

基金项目

supported by the National Natural Science Foundation of China(Grant no.82571048) （Grant no.82571048）

the Guangdong Basic and Applied Basic Research Foundation(Grant no.2026A1515010688)。（Grant no.2026A1515010688）

International Journal of Oral Science

ISSN：1674-2818

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