首页|期刊导航|International Journal of Oral Science|Single-cell transcriptional atlas reveals distinct immune-chondrocyte crosstalk mechanisms in temporomandibular joint osteoarthritis induced by different types of occlusal disorder

Single-cell transcriptional atlas reveals distinct immune-chondrocyte crosstalk mechanisms in temporomandibular joint osteoarthritis induced by different types of occlusal disorder

Kang Wang Yusi Li Shuaixi Xiang Ningyi Shao Peiqi Wang Xianrui Yang Xianglong Han Qingfeng Li Hui Xu

International Journal of Oral Science2026，Vol.18Issue(3)：P.521-532,12.

International Journal of Oral Science2026，Vol.18Issue(3)：P.521-532,12.DOI:10.1038/s41368-025-00424-1

Single-cell transcriptional atlas reveals distinct immune-chondrocyte crosstalk mechanisms in temporomandibular joint osteoarthritis induced by different types of occlusal disorder

Kang Wang ¹Yusi Li ²Shuaixi Xiang ³Ningyi Shao ⁴Peiqi Wang ³Xianrui Yang ⁵Xianglong Han ³Qingfeng Li ⁶Hui Xu³

作者信息

1. State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology,Sichuan University,Chengdu,China Department of Plastic and Burn Surgery,West China Hospital,West China School of Medicine,Sichuan University,Chengdu,China
2. Department of Biomedical Sciences,Faculty of Health Sciences,University of Macao,Taipa,Macao SAR,China The Islands Healthcare Complex-Macao Medical Center of Peking Union Medical College Hospital,Macao SAR,China
3. State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology,Sichuan University,Chengdu,China Department of Orthodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,China
4. Department of Biomedical Sciences,Faculty of Health Sciences,University of Macao,Taipa,Macao SAR,China MoE Frontiers Science Center for Precision Oncology,University of Macao,Taipa,Macao SAR,China Cancer Center,Faculty of Health Sciences,University of Macao,Taipa,Macao SAR,China
5. Department of Orthodontics,University of Florida College of Dentistry,Gainesville,FL,USA
6. Department of Plastic and Reconstructive Surgery,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China
折叠

摘要

关键词

osteoarthritis/single cell transcriptome/temporomandibular joint/cellular signali/condyle cartilage damage/chondrocytes heterogeneity/characterization cellular composition signal networks/progressive degenerative disease

分类

医药卫生

引用本文复制引用

Kang Wang,Yusi Li,Shuaixi Xiang,Ningyi Shao,Peiqi Wang,Xianrui Yang,Xianglong Han,Qingfeng Li,Hui Xu..Single-cell transcriptional atlas reveals distinct immune-chondrocyte crosstalk mechanisms in temporomandibular joint osteoarthritis induced by different types of occlusal disorder[J].International Journal of Oral Science,2026,18(3):P.521-532,12.

基金项目

supported by the National Natural Science Foundation of China(Grant No.81701006,82271018,82371002,32171308) （Grant No.81701006,82271018,82371002,32171308）

the Nature Science Foundation of Sichuan Province(Grant No.2022NSFC0695)。（Grant No.2022NSFC0695）

International Journal of Oral Science

ISSN：1674-2818

访问量0

下载量0

段落导航