首页|期刊导航|International Journal of Oral Science|Single-cell multi-omics sequencing reveals cell-specific transcriptomic and chromatin accessibility profiles in gut microbiome metabolite butyrate-produced pain modulation

Single-cell multi-omics sequencing reveals cell-specific transcriptomic and chromatin accessibility profiles in gut microbiome metabolite butyrate-produced pain modulation

Ran Tao Sufang Liu Joshua Crawford Phillip Kramer Steven Bender Feng Tao

International Journal of Oral Science2026，Vol.18Issue(3)：P.504-520,17.

International Journal of Oral Science2026，Vol.18Issue(3)：P.504-520,17.DOI:10.1038/s41368-026-00432-9

Single-cell multi-omics sequencing reveals cell-specific transcriptomic and chromatin accessibility profiles in gut microbiome metabolite butyrate-produced pain modulation

Ran Tao ¹Sufang Liu ¹Joshua Crawford ¹Phillip Kramer ¹Steven Bender ²Feng Tao¹

作者信息

1. Department of Biomedical Sciences,Texas A&M University School of Dentistry,Dallas,TX,USA
2. Department of Comprehensive Dentistry,Texas A&M University School of Dentistry,Dallas,TX,USA
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摘要

关键词

temporomandibular joint pain/butyrate/gut microbiome/single cell multi omics sequencing/epigenetic regulation/nociceptive processing/histone acetylation/temporomandibular joint tmj disorderswhich

分类

医药卫生

引用本文复制引用

Ran Tao,Sufang Liu,Joshua Crawford,Phillip Kramer,Steven Bender,Feng Tao..Single-cell multi-omics sequencing reveals cell-specific transcriptomic and chromatin accessibility profiles in gut microbiome metabolite butyrate-produced pain modulation[J].International Journal of Oral Science,2026,18(3):P.504-520,17.

基金项目

supported by the National Institutes of Health Grants R01DE031255(F.T.),R01DE032061(F.T.),and R03DE031822(S.L.)。（F.T.）

International Journal of Oral Science

ISSN：1674-2818

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