首页|期刊导航|International Journal of Oral Science|Bioengineered α-Hairpin peptide TKH with GKG linker:a LLPS-mediated biomimetic mineralization system for intrafibrillar remineralization and deep dentin tubule occlusion

Bioengineered α-Hairpin peptide TKH with GKG linker:a LLPS-mediated biomimetic mineralization system for intrafibrillar remineralization and deep dentin tubule occlusion

Yeling Ou Jing Wang Luoyao Wang Haisheng Wang Fengfan He Longjiang Ding Yanping Zhou Sili Han Linglin Zhang

International Journal of Oral Science2026，Vol.18Issue(3)：P.474-487,14.

International Journal of Oral Science2026，Vol.18Issue(3)：P.474-487,14.DOI:10.1038/s41368-026-00425-8

Bioengineered α-Hairpin peptide TKH with GKG linker:a LLPS-mediated biomimetic mineralization system for intrafibrillar remineralization and deep dentin tubule occlusion

Yeling Ou ¹Jing Wang ¹Luoyao Wang ¹Haisheng Wang ²Fengfan He ¹Longjiang Ding ²Yanping Zhou ³Sili Han ¹Linglin Zhang¹

作者信息

1. State Key Laboratory of Oral Diseases&National Centre for Stomatology&National Clinical Research Center for Oral Diseases,West China Hospital of Stomatology,Sichuan University,Chengdu,China Department of Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,China
2. State Key Laboratory of Oral Diseases&National Centre for Stomatology&National Clinical Research Center for Oral Diseases,West China Hospital of Stomatology,Sichuan University,Chengdu,China
3. College of Electronics and Information Engineering,Sichuan University,Chengdu,China
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摘要

关键词

TKH/incorporating flexible gkg linker/dentin hypersensitivity dh originates/dentinal tubules dts patency/desensitizing agentthe/bioengineered peptides/deep tubular occlusionstable/hairpin peptide

分类

医药卫生

引用本文复制引用

Yeling Ou,Jing Wang,Luoyao Wang,Haisheng Wang,Fengfan He,Longjiang Ding,Yanping Zhou,Sili Han,Linglin Zhang..Bioengineered α-Hairpin peptide TKH with GKG linker:a LLPS-mediated biomimetic mineralization system for intrafibrillar remineralization and deep dentin tubule occlusion[J].International Journal of Oral Science,2026,18(3):P.474-487,14.

基金项目

supported by the National Natural Science Foundation of China(No.82370951 to L.L.Z （）

No.82501137 to S.L.H) （）

the Sichuan Science and Technology Program(No.2023ZYD0105 to L.L.Z,No.2026YFHZ0051 to S.L.H)。（No.2023ZYD0105 to L.L.Z,No.2026YFHZ0051 to S.L.H）

International Journal of Oral Science

ISSN：1674-2818

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