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Sex-dependent impact of Il6 deficiency in Parkinson’s disease mice

Fangzheng Chen Yufei Duan Mengze Wang Zhaolin Liu Jiayin Zhao Guangchun Fan Yongtao He Hongtian Dong Xiaoshuang Zhang Rong Fang Yunhe Zhang Xin Ya Chenye Shen Xiwen Tang Yuanyuan Ma Mei Yu Renyuan Zhou Jian Fei Fang Huang

Genes & Diseases2026，Vol.13Issue(4)：P.723-741,19.

Genes & Diseases2026，Vol.13Issue(4)：P.723-741,19.DOI:10.1016/j.gendis.2025.101986

Sex-dependent impact of Il6 deficiency in Parkinson’s disease mice

Fangzheng Chen ¹Yufei Duan ¹Mengze Wang ¹Zhaolin Liu ¹Jiayin Zhao ¹Guangchun Fan ¹Yongtao He ¹Hongtian Dong ¹Xiaoshuang Zhang ¹Rong Fang ¹Yunhe Zhang ¹Xin Ya ¹Chenye Shen ¹Xiwen Tang ¹Yuanyuan Ma ¹Mei Yu ¹Renyuan Zhou ¹Jian Fei ²Fang Huang¹

作者信息

1. Department of Translational Neuroscience,Department of Urology,Jing’an District Centre Hospital of Shanghai,National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science,Institutes of Brain Science,Fudan University,Shanghai 200032,China
2. School of Life Science and Technology,Tongji University,Shanghai 200092,China Shanghai Engineering Research Center for Model Organisms,Shanghai Model Organisms Center,INC.,Pudong District,Shanghai 201203,China
折叠

摘要

关键词

IL-6/MPTP/Neuroinflammation/Parkinson’s disease/rIL-6

分类

医药卫生

引用本文复制引用

Fangzheng Chen,Yufei Duan,Mengze Wang,Zhaolin Liu,Jiayin Zhao,Guangchun Fan,Yongtao He,Hongtian Dong,Xiaoshuang Zhang,Rong Fang,Yunhe Zhang,Xin Ya,Chenye Shen,Xiwen Tang,Yuanyuan Ma,Mei Yu,Renyuan Zhou,Jian Fei,Fang Huang..Sex-dependent impact of Il6 deficiency in Parkinson’s disease mice[J].Genes & Diseases,2026,13(4):P.723-741,19.

基金项目

supported by the National Natural Science Foundation of China(No.32271003) （No.32271003）

the Science and Technology Commission of Shanghai Municipality,China(No.24141901200) （No.24141901200）

the Shanghai Municipal Science and Technology Major Project(China)(No.2018SHZDZX01) （China）

ZJLab,the Shanghai Center for Brain Science and Brain Inspired Technology,the Innovative Research Team of High Level Local University in Shanghai,China. （）

Genes & Diseases

ISSN：2352-4820

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