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ATOX1 overexpression mitigates copper homeostasis in microglia:Implications for Alzheimer''s disease therapy

Fuxin Zhong Jiani Wu Zhangjing Deng Wuhan Yu Jiaqi Song Yingxi Chen Weihua Yu Yang Lu

Genes & Diseases2026，Vol.13Issue(4)：P.677-689,13.

Genes & Diseases2026，Vol.13Issue(4)：P.677-689,13.DOI:10.1016/j.gendis.2025.101888

ATOX1 overexpression mitigates copper homeostasis in microglia:Implications for Alzheimer''s disease therapy

Fuxin Zhong ¹Jiani Wu ¹Zhangjing Deng ¹Wuhan Yu ¹Jiaqi Song ²Yingxi Chen ²Weihua Yu ²Yang Lu¹

作者信息

1. Department of Geriatrics,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China Key Laboratory of Major Brain Disease and Aging Research(Ministry of Education),Chongqing Medical University,Chongqing 400014,China Institute for Brain Science and Disease,Chongqing Medical University,Chongqing 400016,China
2. Institute of Neuroscience,Department of Human Anatomy,Chongqing Medical University,Chongqing 400016,China
折叠

摘要

关键词

Alzheimer’s disease/ATOX1/Copper/Microglia/Oxidative stress

分类

医药卫生

引用本文复制引用

Fuxin Zhong,Jiani Wu,Zhangjing Deng,Wuhan Yu,Jiaqi Song,Yingxi Chen,Weihua Yu,Yang Lu..ATOX1 overexpression mitigates copper homeostasis in microglia:Implications for Alzheimer''s disease therapy[J].Genes & Diseases,2026,13(4):P.677-689,13.

基金项目

supported by grants from the Chongqing Talent Plan(China)(No.cstc2022ycjh-bgzxm0184) （China）

the Key Project of Science and Technology Research Program of Chongqing Municipal Education Commission(China)(No.KJZD-K202200405) （China）

the Innovation Project for Doctoral Students at The First Affiliated Hospital of Chongqing Medical University(China)(No.CYYY-BSYJSCXXM-202320) （China）

the Chongqing Medical Key Discipline and Regional Medical Key Discipline Development Project(China)(0201[2023]No.160202412). （China）

Genes & Diseases

ISSN：2352-4820

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