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Stratified profiling of azoospermia:Differentiating histological subtypes with seminal plasma metabolic signatures

Jiachen Wang Tianyi Song Hongqi Fan Mengyuan Zhu Ying Yao Laihua Li Mingxi Liu Minjian Chen Jiahao Sha Xiaoyu Yang Yan Yuan

The Journal of Biomedical Research2026，Vol.40Issue(4)：P.425-435,I0017,12.

The Journal of Biomedical Research2026，Vol.40Issue(4)：P.425-435,I0017,12.DOI:10.7555/JBR.39.20250294

Stratified profiling of azoospermia:Differentiating histological subtypes with seminal plasma metabolic signatures

Jiachen Wang ¹Tianyi Song ¹Hongqi Fan ²Mengyuan Zhu ³Ying Yao ¹Laihua Li ¹Mingxi Liu ¹Minjian Chen ³Jiahao Sha ¹Xiaoyu Yang ⁴Yan Yuan¹

作者信息

1. State Key Laboratory of Reproductive Medicine and Offspring Health,Nanjing Medical University,Nanjing,Jiangsu 211166,China
2. Department of Endocrinology,the First Affiliated Hospital of Nanjing Medical University,Nanjing Medical University,Nanjing,Jiangsu 210029,China
3. Key Laboratory of Modern Toxicology of Ministry of Education,School of Public Health,Nanjing Medical University,Nanjing,Jiangsu 211166,China
4. State Key Laboratory of Reproductive Medicine and Offspring Health,Clinical Center of Reproductive Medicine,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China
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摘要

关键词

non-obstructive azoospermia/seminal plasma/metabolomics/diagnostic biomarkers

分类

医药卫生

引用本文复制引用

Jiachen Wang,Tianyi Song,Hongqi Fan,Mengyuan Zhu,Ying Yao,Laihua Li,Mingxi Liu,Minjian Chen,Jiahao Sha,Xiaoyu Yang,Yan Yuan..Stratified profiling of azoospermia:Differentiating histological subtypes with seminal plasma metabolic signatures[J].The Journal of Biomedical Research,2026,40(4):P.425-435,I0017,12.

基金项目

funded by the National Key R&D Program(Grant Nos.2022YFC2702800 to Y.Yuan and 2021YFC2700501-1 to L.Li) （Grant Nos.2022YFC2702800 to Y.Yuan and 2021YFC2700501-1 to L.Li）

the National Natural Science Foundation of China(Grant Nos.82221005 to J.Sha and 82201763 to L.Li)。（Grant Nos.82221005 to J.Sha and 82201763 to L.Li）

The Journal of Biomedical Research

ISSN：1674-8301

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