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Atractylenolide I mitigates Alzheimer’s disease pathology in ApoE‑/‑mice via ARG1/nNOS axis and lipid homeostasis regulation

Xun Zhou Rui Wang Jingsi Yan Xiaolang Wu Dongsheng Yuan Qi Wang Huilin Li Wei Zhao

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(5)：P.1155-1169,15.

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(5)：P.1155-1169,15.DOI:10.3724/abbs.2026055

Atractylenolide I mitigates Alzheimer’s disease pathology in ApoE‑/‑mice via ARG1/nNOS axis and lipid homeostasis regulation

Xun Zhou ¹Rui Wang ²Jingsi Yan ³Xiaolang Wu ³Dongsheng Yuan ³Qi Wang ³Huilin Li ⁴Wei Zhao³

作者信息

1. Department of Endocrinology,The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine,Shenzhen 518033,China Department of Endocrinology,Shenzhen Traditional Chinese Medicine Hospital,Shenzhen 518033,China
2. Hospital of Fengnan District Tangshan,Tangshan 063300,China
3. Science and Technology Innovation Center,Guangzhou University of Chinese Medicine,Guangzhou 510405,China
4. Department of Endocrinology,Shenzhen Traditional Chinese Medicine Hospital,Shenzhen 518033,China
折叠

摘要

关键词

Alzheimer’s disease/atractylenolide I/lipid homeostasis/arginine biosynthesis/ApoE‑/‑mice

分类

医药卫生

引用本文复制引用

Xun Zhou,Rui Wang,Jingsi Yan,Xiaolang Wu,Dongsheng Yuan,Qi Wang,Huilin Li,Wei Zhao..Atractylenolide I mitigates Alzheimer’s disease pathology in ApoE‑/‑mice via ARG1/nNOS axis and lipid homeostasis regulation[J].Acta Biochimica et Biophysica Sinica,2026,58(5):P.1155-1169,15.

基金项目

supported by the grants from the National Natural Science Foundation of China(No.81973919) （No.81973919）

the Basic and Applied Basic Research Fund of Guangdong Province(2022A1515220175). （2022A1515220175）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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