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Myocyte enhancer factor 2A orchestrates vascular redox homeostasis via direct transcriptional activation of SIRT1

Benrong Liu Lei Fang Chunxia Miao Xinyu Wen Xiumiao Zheng Minxing Xu Junli Lin Yujuan Xiong Shi-Ming Liu

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(5)：P.1069-1082,14.

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(5)：P.1069-1082,14.DOI:10.3724/abbs.2025163

Myocyte enhancer factor 2A orchestrates vascular redox homeostasis via direct transcriptional activation of SIRT1

Benrong Liu ¹Lei Fang ¹Chunxia Miao ¹Xinyu Wen ¹Xiumiao Zheng ¹Minxing Xu ¹Junli Lin ¹Yujuan Xiong ²Shi-Ming Liu¹

作者信息

1. Department of Cardiology,Guangzhou Institute of Cardiovascular Disease,Guangdong Key Laboratory of Vascular Diseases,State Key Laboratory of Respiratory Disease,the Second Affiliated Hospital,Guangzhou Medical University,Guangzhou 510260,China
2. Department of Laboratory Medicine,Panyu Hospital,Guangzhou University of Chinese Medicine,Guangzhou 511400,China
折叠

摘要

关键词

oxidative stress/MEF2A/redox homeostasis/GSH/GSSG ratio/cardiovascular disease/NADH/NAD+ratio

分类

医药卫生

引用本文复制引用

Benrong Liu,Lei Fang,Chunxia Miao,Xinyu Wen,Xiumiao Zheng,Minxing Xu,Junli Lin,Yujuan Xiong,Shi-Ming Liu..Myocyte enhancer factor 2A orchestrates vascular redox homeostasis via direct transcriptional activation of SIRT1[J].Acta Biochimica et Biophysica Sinica,2026,58(5):P.1069-1082,14.

基金项目

supported by the grants from the Guangzhou Municipal Science and Technology Project(No.2024A03J0940 to B.L.) （No.2024A03J0940 to B.L.）

the Graduate Research Project of the Guangzhou Education Bureau(No.2024312106 to B.L.) （No.2024312106 to B.L.）

the Key Medical Disciplines and Specialties Program of Guangzhou(No.2025‑2027 to S.M.L.) （No.2025‑2027 to S.M.L.）

the Innovation Team of General Universities in Guangdong Province(No.2023KCXTD025 to S.M.L.). （No.2023KCXTD025 to S.M.L.）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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