首页|期刊导航|Acta Biochimica et Biophysica Sinica|Biochemical and structural studies of the midnolin Catch domain bound with both wild-type and mutant IRF4 peptides reveal the molecular basis for its broad substrate specificity

Biochemical and structural studies of the midnolin Catch domain bound with both wild-type and mutant IRF4 peptides reveal the molecular basis for its broad substrate specificity

Yanling Zhong Ziyue Chen Guanchao Wang Jianping Ding

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(6)：P.1235-1249,15.

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(6)：P.1235-1249,15.DOI:10.3724/abbs.2026002

Biochemical and structural studies of the midnolin Catch domain bound with both wild-type and mutant IRF4 peptides reveal the molecular basis for its broad substrate specificity

Yanling Zhong ¹Ziyue Chen ¹Guanchao Wang ¹Jianping Ding²

作者信息

1. State Key Laboratory of RNA Innovation,Science and Engineering,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China
2. State Key Laboratory of RNA Innovation,Science and Engineering,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China School of Life Science and Technology,ShanghaiTech University,Shanghai 201210,China Ruisi Research Center for Life Science,Shanghai 201109,China
折叠

摘要

关键词

structure/midnolin/Catch domain/IRF4/substrate specificity/proteasome

分类

生物科学

引用本文复制引用

Yanling Zhong,Ziyue Chen,Guanchao Wang,Jianping Ding..Biochemical and structural studies of the midnolin Catch domain bound with both wild-type and mutant IRF4 peptides reveal the molecular basis for its broad substrate specificity[J].Acta Biochimica et Biophysica Sinica,2026,58(6):P.1235-1249,15.

基金项目

supported by the grants from the National Key Research and Development Program of China(Nos.2020YFA0509000 and 2020YFA0803200) （Nos.2020YFA0509000 and 2020YFA0803200）

the National Natural Science Foundation of China(No.32071190)。（No.32071190）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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