长春中医药大学学报2026，Vol.42Issue(8)：891-895,5.DOI:10.13463/j.cnki.cczyy.2026.08.003
基于"脾虚瘀毒"理论探讨慢性萎缩性胃炎"炎-癌转化"机制及防治思路
Discussion on the mechanism of inflammation-cancer transformation in chronic atrophic gastritis based on the theory of spleen deficiency and stasis-toxin and its prevention and treatment strategies
摘要
Abstract
Based on the"spleen deficiency and blood stasis toxin"theory,this paper explores the mechanism of"inflammation-cancer transformation"in chronic atrophic gastritis,suggesting that spleen deficiency is the fundamental cause of the disease.Spleen deficiency leads to insufficiency of qi and blood,resulting in the gastric mucosa atrophy due to lack of nourishment;The internal generation of dampness and turbidity,along with the entanglement of dampness and heat,damages stomach collaterals,resulting in inflammatory lesions of the gastric mucosa,which lays the foundation for the accumulation of pathological products of blood stasis and toxins.The coagulation of blood stasis and toxins not only depletes the middle qi and aggravates spleen deficiency,but also accelerates the process of carcinogenesis by damaging the gastric mucosa,promoting intestinal metaplasia,and abnormal hyperplasia.Therefore,based on a deep exploration of the theory of spleen deficiency with blood stasis and toxins,this article proposes that tonifying the spleen and benefiting qi,clearing heat and removing dampness,resolving blood stasis and detoxifying are the main treatment methods.It also explores the preventive and therapeutic effects and mechanisms of related prescriptions and drugs on the"inflammation-cancer transformation"of chronic atrophic gastritis,with the aim of providing new paths for the prevention and treatment of this disease with traditional Chinese medicine.关键词
脾虚瘀毒/慢性萎缩性胃炎/炎-癌转化Key words
spleen deficiency and stasis-toxin/chronic atrophic gastritis/inflammation-cancer transformation分类
医药卫生引用本文复制引用
赵毅,孟昊阳,张思依,黄超群,吕文亮..基于"脾虚瘀毒"理论探讨慢性萎缩性胃炎"炎-癌转化"机制及防治思路[J].长春中医药大学学报,2026,42(8):891-895,5.基金项目
国家自然科学基金青年基金项目(82505321) （82505321）
