长春中医药大学学报2026，Vol.42Issue(8)：901-905,5.DOI:10.13463/j.cnki.cczyy.2026.08.005
基于"脑-肠轴"探讨"运土疏木"理论治疗糖尿病共病抑郁症机制
Discussion on the mechanism of treating diabetes-depression comorbidity with the theory of transporting earth and dredging wood based on the brain-gut axis
摘要
Abstract
Based on the pathogenesis of"earth stagnation leading to wood depression",this study proposes the application of the"transporting earth and dredging wood"method for treating diabetes-depression comorbidity,exploring its intrinsic connection with the regulation of the"gut-brain axis".The pathogenesis of"earth stagnation leading to wood depression"in diabetes-depression comorbidity aligns with the modern medical mechanism of"gut dysbiosis leading to intestinal barrier damage,triggering chronic inflammation,which then induces depression and exacerbates metabolic disorders via the gut-brain axis."The key treatment involves"transporting earth"(strengthening the spleen and resolving dampness)to regulate gut microbiota and reduce inflammatory responses,combined with"dredging wood"(soothing the liver and promoting qi flow)to modulate mood and neuroendocrine function,thereby improving clinical symptoms of diabetes-depression comorbidity.Through mutual verification of Chinese and Western medical theories,this study reveals the scientific connotation of the"transporting earth and dredging wood"method in treating diabetes-depression comorbidity,providing systematic theoretical support for establishing"brain-gut axis"interventions.关键词
糖尿病共病抑郁症/土壅木郁/运土疏木/脑-肠轴Key words
diabetes-depression comorbidity/earth stagnation leading to wood depression/transporting earth and dredging wood/brain-gut axis分类
医药卫生引用本文复制引用
王木子,周姝彤,许铭宇,徐梦可,侯梓轩,郑亚琳,朱智耀,安甜..基于"脑-肠轴"探讨"运土疏木"理论治疗糖尿病共病抑郁症机制[J].长春中医药大学学报,2026,42(8):901-905,5.基金项目
国家自然科学基金青年科学基金项目(82305195) （82305195）
