中国耳鼻咽喉头颈外科2026，Vol.33Issue(6)：343-348,6.DOI:10.16066/j.1672-7002.2026.06.009
远程无感智能睡眠监测系统用于阻塞性睡眠呼吸暂停低通气综合征患者下颌前移矫治器滴定治疗的研究
A study on the remotely contactless intelligent sleep monitoring system for mandibular advancement device titration in patients with obstructive sleep apnea-hypopnea syndrome
摘要
Abstract
OBJECTIVE To validate the efficacy of mandibular advancement device(MAD)titration guided by the remotely contactless intelligent sleep monitoring system(RCISMS)in patients with obstructive sleep apnea hypopnea syndrome(OSAHS).METHODS This study was designed as a randomized controlled trial,after applying inclusion and exclusion criteria,100 patients with moderate to severe OSAHS were enrolled and randomly assigned to the RCISMS objective titration group(n=50)or the subjective titration group(n=50).The RCISMS group underwent MAD titration guided by the RCISMS,while the control group received conventional titration.The apnea-hypopnea index(AHI),lowest oxygen saturation(LSaO₂),and Epworth Sleepiness Scale(ESS)score were recorded before and after treatment.RESULTS The overall response rate in the RCISMS objective titration group was 80.0%(40/50),significantly higher than that in the subjective titration group(56.0%,28/50),the difference was statistically significant(χ²=6.56,P=0.010).The cure rate in the RCISMS objective titration group was 24.0%(12/50),which was higher than that in the subjective titration group(12.0%,6/50).The AHI reduction rate in the RCISMS group(81.4%±9.2%)was significantly higher than that in the subjective titration group(46.9%±13.1%,P<0.001).In terms of titration efficiency,the total titration period in the RCISMS group(28.4±6.3)days was significantly shorter than that in the subjective titration group[(52.6±7.8)days,P<0.001],with a titration efficiency of 52.7%±10.5%.CONCLUSION The RCISMS can significantly improve the efficacy of MAD titration in patients with OSAHS and substantially enhance titration efficiency,demonstrating good clinical application value.关键词
阻塞性睡眠呼吸暂停低通气综合征/下颌前移矫治器/滴定/远程监测Key words
obstructive sleep apnea hypopnea syndrome/mandibular advancement device/titration/remote monitoring引用本文复制引用
雷蕙嘉,朱思翔,杨静,来佑青,王梓敬..远程无感智能睡眠监测系统用于阻塞性睡眠呼吸暂停低通气综合征患者下颌前移矫治器滴定治疗的研究[J].中国耳鼻咽喉头颈外科,2026,33(6):343-348,6.基金项目
北京市医院管理中心临床医学发展专项经费(YGLX202316) （YGLX202316）
