分析化学2026，Vol.54Issue(7)：1218-1227,10.DOI:10.19756/j.issn.0253-3820.261146
基于CoNi双金属有机框架材料比色检测抗坏血酸及总抗氧化能力
Colorimetric Detection of Ascorbic Acid and Total Antioxidant Capacity Based on CoNi Bimetallic Metal-Organic Framework
摘要
Abstract
A CoNi bimetallic metal-organic framework(CoNi-MOF)was synthesized via a room-temperature co-precipitation method.Benefiting from the bimetallic synergistic effect between Co and Ni,CoNi-MOF showed significantly superior oxidase-like(OXD)activity compared with monometallic MOFs,and could catalyze the chromogenic substrate 3,3',5,5'-tetramethylbenzidine(TMB)to produce a color reaction.In the presence of ascorbic acid(AA),the color reaction was markedly inhibited.On this basis,a colorimetric sensing platform for AA detection was constructed.The platform exhibited a linear detection range of 1-16 μmol/L toward AA,with a limit of detection(S/N=3)of 0.34 μmol/L,together with good selectivity and long-term stability.It was successfully applied to analysis of total antioxidant capacity(TAC)in fresh fruits and commercial beverages.The spiked recoveries of passion fruit samples were 98.17%-101.30%,and the relative standard deviations(RSDs)were all below 7%.Without addition of H2O2,this detection system was simple to operate and low in cost,which provided a new analytical method for food quality monitoring and antioxidant capacity evaluation,and expanded new horizons for application of bimetallic MOF nanozymes in sensing analysis.关键词
金属有机框架材料/类氧化酶活性/比色检测/抗坏血酸/总抗氧化能力Key words
Metal-organic frameworks/Oxidase-like activity/Colorimetric detection/Ascorbic acid/Total antioxidant capacity引用本文复制引用
陈羽,张苗苗,唐纪琳..基于CoNi双金属有机框架材料比色检测抗坏血酸及总抗氧化能力[J].分析化学,2026,54(7):1218-1227,10.基金项目
吉林省与中国科学院科技合作高新技术产业化专项项目(No.2022SYHZ0045)和国家自然科学基金项目(No.22405270)资助. Supported by the Special Project for High-tech Industrialization of Science and Technology Cooperation between Jilin Province and Chinese Academy of Sciences(No.2022SYHZ0045)and the National Natural Science Foundation of China(No.22405270). （No.2022SYHZ0045）
