分析化学2026，Vol.54Issue(7)：1228-1236,中插1-中插2,11.DOI:10.19756/j.issn.0253-3820.251233
双酚M分子印迹材料的制备及其在乳制品中双酚类物质富集中的应用
Preparation of Bisphenol M Molecularly Imprinting Materials and Application in Enrichment of Bisphenol Substances in Dairy Products
摘要
Abstract
Molecularly imprinted polymer(MIP)capable of selectively recognizing 14 kinds of bisphenol substances(BPs)was prepared by bulk polymerization using bisphenol M(BPM)as the template molecule and methacrylic acid as the functional monomer.The prepared BPM-MIP was characterized by scanning electron microscopy(SEM)and Brunauer-Emmett-Teller(BET)surface area analysis,indicating that imprint cavities were successfully formed on the material surface.The adsorption capacity of the material under different initial concentrations(5-300 mg/L)was tested through static adsorption experiments,and the Scatchard curve was calculated based on the Scatchard model.A diethylstilbestrol(DEBS)with the same two phenolic hydroxyl structures as BPs was selected as the control substance.The adsorption selectivity of BPM-MIP for 14 kinds of target compounds and DEBS was investigated.BPM-MIP was used for separation and enrichment of BPs in dairy products.The detection was carried out by high performance liquid chromatography(HPLC).At the three spiked concentrations of high(250 μg/kg),medium(50 μg/kg),and low(25 μg/kg)level,the recovery rates of 14 kinds of BPs ranged from 89.6%to 114.2%,and the relative standard deviations(RSDs)were from 1.5%to 5.2%.关键词
分子印迹聚合物/双酚类物质/乳制品/高效液相色谱法/富集Key words
Molecularly imprinted polymers/Bisphenol substances/Dairy products/High performance liquid chromatography/Enrichment引用本文复制引用
邱月,谭超兰,余秋玲,陆嘉莉,龚迎昆..双酚M分子印迹材料的制备及其在乳制品中双酚类物质富集中的应用[J].分析化学,2026,54(7):1228-1236,中插1-中插2,11.基金项目
国家市场监督管理总局科技计划项目(No.2023MK106)和重庆市技术创新与应用发展专项重点项目(No.CSTB2024TIAD-KPX0106)资助. Supported by the National Market Supervision and Administration Bureau Science and Technology Project(No.2023MK106)and Special Project for Technological Innovation and Application Development in Chongqing(No.CSTB2024TIAD-KPX0106). （No.2023MK106）
