核农学报2026，Vol.40Issue(9)：1769-1779,11.DOI:10.11869/j.issn.1000-8551.2026.09.1769
代谢组学揭示60Co-γ与电子束辐照对红参的影响
Effects of 60Co-γ and Electron Beam Irradiation on Red Ginseng(Panax ginseng)Revealed by Metabolomics
摘要
Abstract
In order to investigate the effects of 60Co-γ irradiation and electron beam irradiation on the chemical constituents of red ginseng and further optimize its irradiation processing,red ginseng powder was treated at the absorbed dose ranging from 0 to 100 kGy in this study.A non-targeted metabolomics approach based on the ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry(UPLC-Q-TOF/MS)combined with multivariate statistical methods such as the principal component analysis(PCA)and orthogonal partial least squares discriminant analysis(OPLS-DA)was used to systemically analyze the chemical composition changes and screen for differential markers in red ginseng samples.A total of 59 chemical compounds were identified,including 48 ginsenosides.The results demonstrated that the electron beam irradiation caused less disturbance to the red ginseng metabolome,whereas 60Co-γ irradiation induced significant changes in 37 metabolites,of which 34 were ginsenosides,showing a clear dose-dependent pattern.Both irradiations exerted limited effects on the contents of major ginsenosides(Rg1,Re,and Rb1).Overall,this study revealed that the electron beam irradiation has a milder impact on red ginseng constituents compared with 60Co-γ irradiation,and it provides scientific evidence for optimizing the irradiation processing and quality control of red ginseng products.关键词
红参/化学成分/辐照处理/代谢组学Key words
red ginseng/chemical composition/irradiation/metabolomics分类
轻工纺织引用本文复制引用
许鹏,马吕丽,许凌翔,丁盛,王皓琦,袁佳滢,施申强,傅俊杰..代谢组学揭示60Co-γ与电子束辐照对红参的影响[J].核农学报,2026,40(9):1769-1779,11.基金项目
校企横向基金(中药辐照灭菌质量控制与创新) （中药辐照灭菌质量控制与创新）
