解放军医学杂志2026，Vol.51Issue(7)：989-1002,14.DOI:10.11855/j.issn.0577-7402.0607.2026.0610
高原地区急性肺血栓栓塞症诊断与治疗专家共识
Expert consensus on diagnosis and treatment of acute pulmonary thromboembolism in high-altitude regions
摘要
Abstract
Extreme natural environments in high-altitude regions can significantly increase the risk of acute pulmonary thromboembolism(PTE).Clinical manifestations of acute PTE in these regions often overlap with those of conditions such as high-altitude pulmonary edema and pneumonia.Moreover,common biomarkers including D-dimer exhibit reduced specificity due to high-altitude physiological adaptation,while clinical assessment tools validated for low-altitude populations may not be applicable here.Coupled with relatively limited medical resources,these factors lead to diagnostic difficulties and inaccurate risk stratification.Although the standard management principles for pulmonary embolism are generally followed,special problems exist,such as increased bleeding risk associated with thrombolysis in hypoxic high-altitude environments and delayed patient transfer.Therefore,the diagnosis,differential diagnosis,and treatment of this disease in high-altitude regions face severe challenges.To address these issues,the Military Clinical Key Specialty(High-Altitude Medicine),Ministry of Education Key Laboratory of Extreme Environmental Medicine,Key Laboratory of Military Logistics Scientific Research,Military Key Laboratory of High-Altitude and Cold Environment Medical Support,and the Army Trauma and Cardiovascular Disease Specialist Alliance took the lead in convening experts nationwide from fields including high-altitude medicine,cardiology,vascular surgery,emergency medicine,critical care medicine,and respiratory and critical care medicine to jointly develop the"Expert consensus on diagnosis and treatment of acute pulmonary thromboembolism in high-altitude regions".This consensus covers four sections on acute PTE in high-altitude regions:epidemiology and pathogenesis,diagnosis,treatment,as well as prevention and follow-up,with a total of 16 recommendations.It puts forward specific suggestions on risk stratification,individualized treatment,prevention strategies,and long-term follow-up,aims to guide the prevention,treatment,and research of acute PTE under special high-altitude environments.关键词
高原地区/急性肺血栓栓塞症/诊断/治疗/共识Key words
high-altitude regions/acute pulmonary thromboembolism/diagnosis/treatment/consensus分类
医药卫生引用本文复制引用
张辰,全军临床重点专科(高原医学),极端环境医学教育部重点实验室,军队后勤科研重点实验室,高原高寒医学保障军队重点实验室,陆军战创伤心血管病专科联盟,李丽,李小庆,唐思,李平,王勇,王伟,晋军,于世勇..高原地区急性肺血栓栓塞症诊断与治疗专家共识[J].解放军医学杂志,2026,51(7):989-1002,14.基金项目
This work was supported by the Scientific Research Assistance Project of the"Key Specialty Development Program"(KYXZ02) 重点培育专科建设科研协助项目(KYXZ02) （KYXZ02）
