经济动物学报2026，Vol.30Issue(4)：253-259,7.DOI:10.13326/j.jea.2026.2017
IGF1R基因拷贝数变异与不同品种牛生长性状的关联
IGF1R Gene Copy Number Variation Associated with Growth Traits in Different Cattle Breeds
摘要
Abstract
Copy number variation(CNV)is an important form of genetic variation.Insulin-like growth factor 1 receptor(IGF1R)is associated with bone development and muscle cell proliferation,and IGF1R CNV is associated with growth performance in Northwestern Yellow cattle.In order to investigate the correlation between IGF1R CNV and growth traits of cattle breeds in Northeast China,the qRT-PCR method was used to detect the distribution and mRNA expression level of IGF1R CNV,and correlation analysis was performed between CNV and growth traits of Grassland Red cattle,Yanbian cattle,and Yan Yellow cattle.The results showed that IGF1R had different types of CNVs in different breeds of cattle,and IGF1R CNVs were significantly correlated with body weight,body height,hip height,body slanting length,chest girth,abdominal girth,hip width,rump width and eye muscle area of Grassland Red cattle,backfat thickness of Yanbian cattle,and body weight,body height,hip height,and chest girth of Yan Yellow cattle(P<0.05).In conclusion,IGF1R CNV is significantly correlated with growth traits of cattle breeds in Northeast China and can serve as a molecular marker for cattle breeding in this area.关键词
拷贝数变异/IGF1R/草原红牛/延边牛/延黄牛Key words
copy number variation/IGF1R/Grassland Red cattle/Yanbian cattle/Yan Yellow cattle分类
农业科技引用本文复制引用
刘基伟,赵玉民,吴健,罗晓彤,李轩宇,刘洪亮,张聪聪,韩越,李春宇,李胜男,李瑞冬..IGF1R基因拷贝数变异与不同品种牛生长性状的关联[J].经济动物学报,2026,30(4):253-259,7.基金项目
国家肉牛牦牛产业技术体系项目(CARS-37),雪花牛肉提质增量生产技术集成与示范项目(2024),吉林省肉牛专项(YDZJ202203CGZH044),肉牛遗传资源开发利用及科技提质增效项目(202402),吉林省农业科学院创新工程项目(CXGC2022RCG007) （CARS-37）
