临床口腔医学杂志2026，Vol.42Issue(7)：401-404,4.DOI:10.3969/j.issn.1003-1634.2026.07.005
牙髓再生治疗在年轻恒牙慢性根尖周炎中的临床应用
Clinical application of regenerative endodontic therapy in immature permanent teeth with chronic apical peri-odontitis
摘要
Abstract
Objective:To compare the clinical efficacy of pulp regeneration therapy versus apexification in the treat-ment of chronic periapical periodontitis involving immature permanent teeth.Methods:A total of 40 pediatric patients(with 40 affected immature permanent teeth)diagnosed with chronic periapical periodontitis who were admitted to our hospital from March 2024 to March 2025 were enrolled.Based on the principle of informed consent obtained from the guardians,the pa-tients were divided into two groups:the experimental group(22 teeth)received pulp regeneration therapy,while the control group(18 teeth)received apexification.All patients were followed up for 12 months postoperatively.Changes in root develop-ment,root canal wall thickness,and root length of the affected teeth were observed and compared between the two groups.Re-sults:The increases in root canal wall thickness and root length in the experimental group were statistically significant com-pared with those in the control group(P<0.05).Root development in the pulp regeneration therapy group was significantly superior to that in the apexification group,and the difference was statistically significant(P<0.05).Conclusion:In the clini-cal management of chronic periapical periodontitis in immature permanent teeth,pulp regeneration therapy is more effective than apexification in promoting continued root development.关键词
年轻恒牙/牙髓再生治疗/根尖诱导成形术/氢氧化钙糊剂/iRoot BP PlusKey words
Immature permanent teeth/Pulp regeneration therapy/Apexification/Calcium hydroxide paste/iRoot BP Plus分类
医药卫生引用本文复制引用
刘金蓉,胡倩倩..牙髓再生治疗在年轻恒牙慢性根尖周炎中的临床应用[J].临床口腔医学杂志,2026,42(7):401-404,4.基金项目
荆门市一般科技计划项目(2024YFYB014) （2024YFYB014）
