皮肤性病诊疗学杂志2026，Vol.33Issue(7)：512-518,7.DOI:10.3969/j.issn.1674-8468.2026.07.005
手足湿疹样表现的蕈样肉芽肿1例并文献复习
Mycosis fungoides with palmoplantar eczema-like manifestations:A case report and litera-ture review
许瑶函 1米泽曦 1Esmeraldito Ferreira 1陈永锋2
作者信息
- 1. 南方医科大学,广东 广州 510515||南方医科大学皮肤病医院,广东 广州 510091
- 2. 南方医科大学皮肤病医院,广东 广州 510091
- 折叠
摘要
Abstract
Objective To investigate the clinical features,diagnostic clues,and management of mycosis fungoides(MF)presenting with palmoplantar eczema-like lesions.Methods A retro-spective analysis of the clinical data of a patient with MF initially misdiagnosed as palmoplantar ec-zema was conducted.Diagnosis was confirmed by histopathology from multiple sites,immunohisto-chemistry,and T-cell receptor(TCR)gene rearrangement analysis.Results The patient had a 4-year history of refractory palmoplantar lesions and had failed multiple systemic therapies.Re-peated biopsies confirmed MF.Treatment with methotrexate,combined with local radiotherapy and phototherapy,resulted in marked improvement in erythema,infiltration,and scaling.Conclusions MF should be considered if a patient has chronic palmoplantar eczema-like lesions that are per-sistent or treatment-resistant.Immunophenotyping and TCR clonality analysis of the repeated biop-sies are necessary for accurate diagnosis and timely treatment.关键词
手足湿疹/蕈样肉芽肿/组织病理/文献复习Key words
palmoplantar eczema/mycosis fungoides/histopathology/literature review引用本文复制引用
许瑶函,米泽曦,Esmeraldito Ferreira,陈永锋..手足湿疹样表现的蕈样肉芽肿1例并文献复习[J].皮肤性病诊疗学杂志,2026,33(7):512-518,7.
