南京中医药大学学报2026，Vol.42Issue(8)：1138-1144,7.DOI:10.14148/j.issn.1672-0482.2026.1138
国医大师皮持衡从"脾家实,腐秽当去"辨治糖尿病肾脏病经验
Master of Traditional Chinese Medicine Pi Chiheng's Experience of Clinical Diagnosis and Treatment of Diabetic Kidney Disease Based on the Principle of"Robust Spleen System Expelling Putrid Waste"
摘要
Abstract
"Robust spleen system expelling putrid waste"originates from Treatise on Cold Damage,and its core meaning lies in the fact that when the spleen and stomach functions are robust,putrid waste will naturally be eliminated.Master of Traditional Chinese Medicine Pi Chiheng offers an innovative interpretation of this classic theory:on the one hand,he systematically expounded the physi-ological functions of the rise and fall,reception and transformation,dryness and dampness of spleen and stomach qi;on the other hand,he provides a scientific explanation from the perspective of the modern"gut-kidney axis"mechanism.He also points out that although diabetic kidney disease(DKD)affects the kidneys,the spleen is crucial.He proposes that"spleen deficiency,yang deficiency and yin depletion,and accumulation of putrid waste"are the core pathogenesis of DKD.Among these,spleen deficiency is the initial stage of the disease,yang deficiency and yin depletion are the key to its progression,and the accumulation of putrid waste is the final result.Clinical diagnosis and treatment are based on the fundamental principle of"balancing and unblocking the spleen and stomach qi trans-formation,and eliminating putrid waste and stagnation".This leads to four major diagnostic approaches:balancing and regulating the pivot to restore the rise and fall,harmonizing the circulation of Ying Wei to regulate the entering and leaving,strengthening the fire and earth to aid the reception and transformation,and regulating water and fire to balance dryness and dampness.This has formed the for-mation of distinctive compatibility rules and representative drug pairs based on the yin-yang theory of the spleen system,providing new ideas and references for the traditional Chinese medicine diagnosis and treatment of DKD.关键词
脾家实/腐秽/脾胃气化/糖尿病肾脏病/皮持衡/名医经验Key words
robust spleen system/putrid waste/spleen and stomach qi transformation/diabetic kidney disease/Pi Chiheng/re-nowned physician experience分类
医药卫生引用本文复制引用
李福生,李地洋,王茂泓,宋卫国,李天盛,吴国庆..国医大师皮持衡从"脾家实,腐秽当去"辨治糖尿病肾脏病经验[J].南京中医药大学学报,2026,42(8):1138-1144,7.基金项目
皮持衡国医大师传承工作室建设项目(赣财社指2022[56]号) （赣财社指2022[56]号）
国家自然科学基金地区科学基金项目(82160879,82460873) （82160879,82460873）
江西省中医药管理局科技计划项目(2024B0005) （2024B0005）
