南京中医药大学学报2026，Vol.42Issue(8)：1153-1160,8.DOI:10.14148/j.issn.1672-0482.2026.1153
经方本原剂量传承偏差的思考与探索
Reflections and Explorations on Discrepancies in the Transmission of Original Dosages of Classic Formulas
摘要
Abstract
The accurate understanding and rational transmission of original dosages of classic formulas remain central to the inheri-tance and development of traditional Chinese medicine(TCM).During the transmission process,discrepancies in these original dosages have gradually emerged due to factors such as changes in systems of weights and measures,distortions associated with non-standard measurement units,errors,disarray,confusion,and omissions in textual transmission,and variations in medicinal material origins,pro-cessing methods,decoction techniques,and substitute applications.This paper systematically summarizes the primary causes of these transmission discrepancies and analyzes the pathways through which modern research validates these issues,covering aspects such as metrological verification,dose-effect-toxicity studies,clinical dosage comparisons,research on processing and dosage forms,and ex-pert consensus.The issue of original dosages of classic formulas is not merely a matter of converting ancient measurements to modern equivalents.It should be based on the analysis of the medicinal material origins,combined with historical research,experimental evalu-ation,clinical evidence,and modern standards,to understand the scope of application of classic dosages under contemporary conditions in a layered manner.Future efforts should focus on gradually establishing a dynamic application system for dosages of classic formulas that balances historical evidence,modern validation,and clinical safety.关键词
经方本原剂量/历代度量衡/量效关系/现代研究Key words
original dosages of classic formulas/historical weights and measures/dose-effect relationship/modern research分类
医药卫生引用本文复制引用
吴欣璐,鲍婷婷,王思成,于同月,赵林华..经方本原剂量传承偏差的思考与探索[J].南京中医药大学学报,2026,42(8):1153-1160,8.基金项目
中国中医科学院科技创新工程(CI2021A01605) （CI2021A01605）
代谢性疾病研究专项项目(DXZX-04-03) （DXZX-04-03）
