兽类学报2026，Vol.46Issue(4)：561-574,14.DOI:10.16829/j.slxb.151049
基于转录组数据挖掘塔里木马鹿干旱环境适应性相关基因
Mining genes related to drought adaptation in Cervus elaphus yarkanden-sis based on transcriptome data
摘要
Abstract
Cervus elaphus yarkandensis have adapted to extreme arid conditions in the Tarim Basin,such as severe drought,high temperatures,and intense ultraviolet radiation.To investigate their adaptation mechanisms,we conducted a comparative transcriptome analysis on the skin tissues of C.e.yarkandensis and C.e.xanthopygus using RNA-seq technology.Our analysis identified 3 562 differentially expressed genes,including 1 279 upregulated genes and 2 283 downregulated genes.Upregulated genes were significantly enriched in 174 GO categories,including regulating water loss through the skin,establishing skin barriers,water balance,and 49 KEGG pathways,such as steroid hormone biosyn-thesis,asthma,and arachidonic acid metabolism.Downregulated genes were significantly enriched in 453 GO catego-ries,including regulation of developmental processes,angiogenesis development,blood pressure regulation,and 60 KEGG pathways such as platelet activation and vascular smooth muscle contraction,and ECM-receptor interaction.qRT-PCR analysis confirmed the reliability of the RNA-seq results.These differentially expressed genes related to skin protection,moisture control,and stress responses likely help the species adapt to arid conditions by maintaining body temperature and preventing water loss.关键词
塔里木马鹿/适应性/干旱环境/差异表达基因/RNA测序Key words
Cervus elaphus yarkandensis/Adaptation/Arid environment/Differentially expressed genes/RNA-Seq分类
生物科学引用本文复制引用
布威海丽且姆·阿巴拜科日,古丽米热·安外尔,钟林强,赵华斌..基于转录组数据挖掘塔里木马鹿干旱环境适应性相关基因[J].兽类学报,2026,46(4):561-574,14.基金项目
新疆维吾尔自治区自然科学基金(2022D01B40) （2022D01B40）
新疆和田学院校级科研培育项目(2025ZR008) （2025ZR008）
