实用中医药杂志2026，Vol.42Issue(7)：1269-1272,4.DOI:10.3969/j.issn.1004-2814.2026.07.002
槐花散合葛根芩连汤治疗急性放射性直肠损伤临床观察
邢陈 1吴春艳2
作者信息
- 1. 江苏省盐城市第二人民医院,江苏 盐城 224003
- 2. 江苏省盐城市第七人民医院,江苏 盐城 224050
- 折叠
摘要
Abstract
Objective:To observe the therapeutic effect of Huaihua Powder combined with Gegen Qinlian Decoction on acute radiation-induced rectal injury.Methods:Ninety patients were randomly divided into an observation group and a control group,with 45 cases in each.The control group received oral Bifidobacterium triple viable capsules and suppository of sulfasalazine per anum,while the observation group was treated with retention enema of Huaihua Powder combined with Gegen Qinlian Decoction.Results:After treatment,there was no statistically significant difference in the total effective rate between the two groups(P>0.05).Traditional Chinese medicine(TCM)syndrome scores decreased in both groups(P<0.05),and the scores for bloody purulent stool,tenesmus,anal burning sensation,and abdominal pain in the observation group were lower than those in the control group(P<0.05).The proportion of patients with RTOG grade 0 radiation-induced rectal injury in the observation group was higher than that in the control group(P<0.05).Serum levels of IL-1 and IL-6 decreased in both groups with a greater reduction in the observation group(P<0.05).No significant adverse reactions occurred in either group.Conclusion:Retention enema with Huaihua Powder combined with Gegen Qinlian Decoction could effectively alleviate symptoms of acute radiation-induced rectal injury,reduce inflammatory markers,and is safe.关键词
急性放射性直肠损伤/槐花散/葛根芩连汤Key words
Acute radiation-induced rectal injury/Huaihua Powder/Gegen Qinlian Decoction分类
医药卫生引用本文复制引用
邢陈,吴春艳..槐花散合葛根芩连汤治疗急性放射性直肠损伤临床观察[J].实用中医药杂志,2026,42(7):1269-1272,4.
