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海洋中药传承创新关键科学问题、研究策略与发展目标

侯小涛 邱倩倩 韦雪丹 宋艳辉 邓家刚 郝二伟 杜正彩 侯万超 郭娟 付先军 陈娟林 韦凤尧

中草药2026,Vol.57Issue(14):5353-5367,15.
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中草药2026,Vol.57Issue(14):5353-5367,15.DOI:10.7501/j.issn.0253-2670.2026.14.001

海洋中药传承创新关键科学问题、研究策略与发展目标

Key scientific questions,research strategies,and development goals for inheritance and innovation of marine traditional Chinese medicine

侯小涛 1邱倩倩 1韦雪丹 1宋艳辉 1邓家刚 2郝二伟 2杜正彩 2侯万超 1郭娟 3付先军 4陈娟林 1韦凤尧1

作者信息

  • 1. 广西中医药大学 广西中药药效研究重点实验室,广西 南宁 530200||广西中医药大学 中药资源循环利用广西高校工程研究中心,广西 南宁 530200||广西中医药大学 广西中医湿病方药理论与转化重点实验室,广西 南宁 530200||广西中医药大学药学院,广西 南宁 530200
  • 2. 广西中医药大学 广西中药药效研究重点实验室,广西 南宁 530200||广西中医药大学 中药资源循环利用广西高校工程研究中心,广西 南宁 530200||广西中医药大学 广西中医湿病方药理论与转化重点实验室,广西 南宁 530200
  • 3. 中国中医科学院中药资源中心 道地药材国家重点实验室培育基地,北京 100700
  • 4. 山东中医药大学海洋中药研究院/国家中医药管理局海洋中药新药发现与开发重点研究室/山东省高等学校海洋中药重点实验室,山东 济南 250355
  • 折叠

摘要

Abstract

Marine traditional Chinese medicine(MTCM),as an important component of the traditional Chinese medicine system,has long been utilized for disease prevention,therapy,and health maintenance due to its unique biological origins and diverse pharmacological properties.China possesses abundant and distinctive marine biological resources,with more than 700 verifiable marine medicinal materials recorded in classical literature,including algae,shellfish,fish,and marine minerals,indicating substantial developmental potential.However,compared with terrestrial traditional Chinese medicines,the modernization of MTCM has started relatively late.Significant gaps remain in resource investigation,pharmacological interpretation,quality control systems,processing technologies,innovative product development,and industrial chain construction.Based on a systematic analysis,this review identifies four major scientific challenges currently hindering the development of MTCM:First,insufficient modern research and inadequate transformation of traditional knowledge.Second,low resource utilization efficiency,accompanied by ecological pressure and endangerment risks.Third,a predominant focus on chemical isolation with limited integration of traditional Chinese medical theory.Fourth,a shortage of high-level interdisciplinary talent and weak innovation systems.To address these bottlenecks,this study propose an integrated development framework spanning"resources-pharmacology-quality-processing-products-industry".Key strategies include comprehensive resource surveys and database construction,integration of traditional medicinal theory with modern pharmacology,establishment of quality markers and safety evaluation systems,development of advanced processing and extraction technologies,and innovation in formulations and health products.Furthermore,phased development goals for MTCM are proposed.In the short term,priorities include resource investigation,standard system establishment,and efficacy evaluation.In the long term,efforts should focus on building a complete industrial chain and an internationalized research and development system to achieve large-scale industrialization and global expansion.Overall,MTCM holds significant promise under the"Healthy China 2030"initiative and within the global health industry.Through systematic planning and collaborative innovation,it is expected to advance toward systematization,modernization,and internationalization.

关键词

海洋中药/中药现代化/资源利用/质量控制/产业发展

Key words

marine traditional Chinese medicine/traditional Chinese medicine modernization/resource utilization/quality control/industrial development

分类

医药卫生

引用本文复制引用

侯小涛,邱倩倩,韦雪丹,宋艳辉,邓家刚,郝二伟,杜正彩,侯万超,郭娟,付先军,陈娟林,韦凤尧..海洋中药传承创新关键科学问题、研究策略与发展目标[J].中草药,2026,57(14):5353-5367,15.

基金项目

广西中医药大学"桂派中医药传承创新团队"项目(2022A005) (2022A005)

"尖锋"行动计划(广西重大专项计划)项目"南珠资源综合利用研究与中成药产品二次开发"(桂科 JF2503980037) (广西重大专项计划)

广西海洋中药资源及标准调研(桂药监科[2023]001号) (桂药监科[2023]001号)

中草药

0253-2670

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