中国临床药学杂志2026，Vol.35Issue(6)：524-530,7.DOI:10.19577/j.1007-4406.2026.06.008
734例次感染性疾病会诊病例的临床药师干预效果与影响因素
Effectiveness of clinical pharmacist interventions and influencing factors in 734 consultation cases of infectious diseases
摘要
Abstract
AIM To evaluate the effectiveness of clinical pharmacist involvement in infectious disease consultations and to analyze factors influencing antimicrobial treatment outcomes,providing evidence for optimizing pharmaceutical services.METHODS A retrospective analysis was conducted on cases involving clinical pharmacists in anti-infective consultations at a hospital between January and December 2024.The acceptance rate of suggestions raised by clinical pharmacists in anti-infective consultation was used as the primary measure,and the clinical response rate was used as the study outcome.Patients were divided into an adoption group and a non-adoption group based on whether the consultation recommendations were adopted,and the clinical outcomes were compared between 2 groups.The multivariate logistic regression model was employed to analyze factors influencing clinical treatment outcomes(treatment efficacy and treatment inefficacy).RESULTS A total of 734 cases of infectious disease consultations were ultimately included.The purpose of clinical pharmacist consultation for anti-infective therapy primarily revolved around the selection of anti-infective drugs,accounting for 74.39％.A total of 635 anti-infective treatment consultation recommendations were adopted,with an adoption rate of 86.15％.The treatment efficacy rate in the adoption group demonstrated a statistically significant difference compared to the non-adoption group(86.68％vs 26.67％,P＜0.05).Multivariate logistic regression analysis identified that hypoalbuminemia and tumor diseases emerged as statistically validated risk factors for treatment inefficacy in anti-infective consultations involving clinical pharmacists,whereas single-discipline consultations,availability of microbiological testing,and adoption of clinical pharmacists' recommendations demonstrated significant protective effects correlated with therapeutic success(P＜0.05).CONCLUSION Clinical pharmacists' participation in infectious disease consultations plays a significant role in optimizing therapeutic protocols and improving patient clinical outcomes.关键词
临床药师/感染性疾病/药学会诊/影响因素Key words
clinical pharmacist/infectious diseases/pharmaceutical consultation/influencing factors分类
医药卫生引用本文复制引用
王昆,刘俊保,董利森,郭敏,汪岑,徐磊,苏长海..734例次感染性疾病会诊病例的临床药师干预效果与影响因素[J].中国临床药学杂志,2026,35(6):524-530,7.基金项目
鄂尔多斯市财政资助医学重点学科建设项目(鄂卫健发[2020]230号) （鄂卫健发[2020]230号）
