中国中药杂志2026，Vol.51Issue(13)：3687-3696,10.DOI:10.19540/j.cnki.cjcmm.20260416.302
基于主成分分析的中药粉体流动性多维度综合评价体系构建与应用
Development and application of multidimensional comprehensive evaluation system for flowability of TCM powders based on principal component analysis
摘要
Abstract
To address the problem that conventional evaluation methods struggle to comprehensively characterize the complex flow behavior of TCM powders,this study utilized an FT4 powder rheometer to perform a multidimensional characterization of 24 representative samples,including decoction pieces,extracts,excipients,and granules.In addition to traditional static parameters like angle of repose(α)and Carr index(IC),the study focused on dynamic rheological characteristics,specifically basic flow energy(BFE)and flow rate index(FRI),alongside shear and bulk property indicators such as cohesion(Co)and flow function coefficient(FFc).Data analysis revealed that individual indicators frequently yield conflicting assessments for the same sample,underscoring the dimensional limitations of isolated metrics.By leveraging correlation analysis and principal component analysis(PCA),the study extracted core contributing factors to construct a weighted flowability comprehensive index(FCI).The results indicated that the FCI successfully integrated multi-source heterogeneous data,showing strong alignment with core flowability parameters and enabling precise classification of powder flow grades.This index offers a robust quantitative framework for enhancing stability assessment and quality control in TCM powder preparation processes.关键词
FT4粉体流变仪/中药粉体/流动性/多元统计分析/表征方法Key words
FT4 powder rheometer/TCM powder/flowability/multivariate statistical analysis/characterization methods引用本文复制引用
胡恢权,万鑫浩,刘英,胡慧,刘宇豪,李远辉,彭常春,伍振峰..基于主成分分析的中药粉体流动性多维度综合评价体系构建与应用[J].中国中药杂志,2026,51(13):3687-3696,10.基金项目
国家重点研发计划项目(2023YFC3504504) （2023YFC3504504）
江西省"科技+中医药"联合项目(2023KZI01009) （2023KZI01009）
