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胆类中药的化学成分及药理作用研究进展

卢婉怡 楼剑书 丁丽丽 王汛江 庄童喜 张玉雯 李航希 郝龙龙 王旭 王峥涛 杨莉

中国中药杂志2026,Vol.51Issue(14):3917-3928,12.
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中国中药杂志2026,Vol.51Issue(14):3917-3928,12.DOI:10.19540/j.cnki.cjcmm.20260420.301

胆类中药的化学成分及药理作用研究进展

Research progress on chemical constituents and pharmacological activities of animal gallbladder-derived TCMs

卢婉怡 1楼剑书 2丁丽丽 3王汛江 3庄童喜 3张玉雯 2李航希 3郝龙龙 3王旭 3王峥涛 3杨莉3

作者信息

  • 1. 杭州师范大学 药学院,浙江省全省抗癌中药与天然药物重点实验室,浙江 杭州 311121||上海中医药大学 中药研究所,中药功效成分发掘与利用全国重点实验室,中药标准化教育部重点实验室,中药新资源与品质评价国家中医药管理局重点研究室,上海市复方重点实验室,上海 201203
  • 2. 杭州师范大学 药学院,浙江省全省抗癌中药与天然药物重点实验室,浙江 杭州 311121
  • 3. 上海中医药大学 中药研究所,中药功效成分发掘与利用全国重点实验室,中药标准化教育部重点实验室,中药新资源与品质评价国家中医药管理局重点研究室,上海市复方重点实验室,上海 201203||上海中药标准化研究中心,上海 201203
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摘要

Abstract

Animal gallbladder-derived TCMs,such as those from pigs,bears,snakes,and chickens,are rich in constituents including bile acids,proteins,amino acids,and trace elements.They have been traditionally used for their properties in clearing heat,detoxifying,relieving cough,and improving vision.This article systematically reviewed the chemical composition and pharmacological activities of animal gallbladder-derived TCMs.It focused on elucidating the molecular mechanisms through which their active components exerted anti-inflammatory,hepatoprotective,and glucolipid metabolism-regulating effects,primarily by modulating nuclear and membrane receptors,influencing ion channels,and regulating related signaling pathways.Comparisons of similarities and differences among medicinal materials from various sources were also presented.This review aimed to provide a theoretical basis for the modern research and clinical translation of this category of TCMs.

关键词

胆类中药/化学成分/药理作用

Key words

animal gallbladder-derived TCM/chemical constituents/pharmacological activities

引用本文复制引用

卢婉怡,楼剑书,丁丽丽,王汛江,庄童喜,张玉雯,李航希,郝龙龙,王旭,王峥涛,杨莉..胆类中药的化学成分及药理作用研究进展[J].中国中药杂志,2026,51(14):3917-3928,12.

基金项目

国家自然科学基金联合基金项目(U24A20792,U24A20775) (U24A20792,U24A20775)

国家自然科学基金项目(82274165,82505115) (82274165,82505115)

中国中药杂志

1001-5302

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