中国中药杂志2026,Vol.51Issue(15):4257-4267,11.DOI:10.19540/j.cnki.cjcmm.20260430.303
中药活性成分纳米递送系统治疗肾脏疾病的研究进展
Research progress in nano-delivery systems of active ingredients in TCM for treating kidney diseases
摘要
Abstract
Kidney diseases,with rising incidences,pose a serious challenge to global public health.Modern medical treatments exhibit numerous limitations,while TCM approaches for kidney diseases face low bioavailability and insufficient targeting.The unique physicochemical properties of nanoparticles enable nanoparticle drug delivery systems(NDDS)to achieve precise targeting of TCM active ingredients for kidney diseases through passive and active targeting strategies.This paper systematically describes the definition,classification,physicochemical factors,and core advantages of NDDS.Furthermore,it summarizes the applications and mechanisms of NDDS in various kidney diseases and discusses the challenges and future prospects for clinical translation.This review aims to establish a novel path for the precision treatment of kidney diseases with TCM.关键词
纳米递送系统/中药活性成分/肾脏疾病/靶向递送Key words
nano-delivery systems/active ingredients of TCM/kidney diseases/targeted delivery引用本文复制引用
陈正,陈至,卢志强,谭红艳,陈金莲,胡淑娟,彭亚军..中药活性成分纳米递送系统治疗肾脏疾病的研究进展[J].中国中药杂志,2026,51(15):4257-4267,11.基金项目
湖南省自然科学基金项目(2023JJ30473) (2023JJ30473)
湖南省卫生健康科研课题(20256869,20257025) (20256869,20257025)