动物医学进展2026，Vol.47Issue(8)：57-64,8.
菊苣水提物对雏鸡生长性能及部分免疫、肝肾和肠道功能的影响
Effects of Cichorium intybus L.Aqueous Extract on Growth Performance,Partial Immunity,Liver and Kidney Functions and Intestinal Function of Chicks
摘要
Abstract
This study aimed to investigate the effects of Cichorium intybus L.aqueous extract on the growth performance,immunity,liver and kidney function,and intestinal function of 6-day-old chickens,with flor-fenicol as the control,providing new options for the practice of reducing and substituting antibiotics in tra-ditional Chinese veterinary medicine.The chickens were randomly divided into a blank control group(A),a florfenicol group(B),and low(C),medium(D),and high(E)dose groups of Cichorium intybus L.aque-ous extract.The test lasted for 6 days,during which serum,immune organs,liver,kidney,and intestinal tis-sue samples were collected to detect relevant indicators.The results showed that at 6 days of age,compared with the control group,the florfenicol group exhibited significantly higher feed conversion ratio(F/G),hepatorenal index,serum aspartate aminotransferase(AST),alanine aminotransferase(ALT),uric acid,u-rea nitrogen,creatinine,liver tumor necrosis factor-α(TNF-α),and malondialdehyde(MDA)levels(P＜0.05),while average daily gain(ADG),average daily feed intake(ADFI),bursa of Fabricius index,serum immunoglobulin G(IgG)and immunoglobulin M(IgM)levels,jejunal villus height(VH),villus height to crypt depth ratio(V/C),and lipase activity were significantly reduced(P＜0.05).In the low-dose group,ADG,serum IgG,jejunal V/C,and amylase activity were significantly increased(P＜0.05).In the medium-dose group,ADG,ADFI,thymus index,serum immunoglobulin A(IgA)and IgG levels,jejunal V/C,amyl-ase activity,and chymotrypsin activity were significantly increased(P＜0.05).Liver MDA levels were sig-nificantly reduced in the low-and medium-dose groups(P＜0.05).Jejunal amylase activity was significantly increased in the high-dose group(P＜0.05).These results indicated that substituting Cichorium intybus L.aqueous extract for florfenicol in the drinking water of chickens can increase growth performance,enhance immune function,maintain hepatorenal health,and improve intestinal function,with the 2.5 g/L dose showing the best effect.关键词
菊苣水提物/生长性能/免疫力/肝肾功能/肠道功能Key words
Cichorium intybus L.aqueous extract/Growth performance/Immunity/Liver and kidney func-tions/Intestinal function分类
农业科技引用本文复制引用
魏明宇,史万玉,包永占,王霄,张珊珊,陈一凡,赵泽华,乔若晗,樊思嘉,李若贤,汤络祁,豆豆..菊苣水提物对雏鸡生长性能及部分免疫、肝肾和肠道功能的影响[J].动物医学进展,2026,47(8):57-64,8.基金项目
"十四五"国家重点研发计划项目(2022YFD1801104) （2022YFD1801104）
河北省自然科学基金专项(C2025204153) （C2025204153）
河北省现代农业产业技术体系创新团队建设专项(HBCT2024110202) （HBCT2024110202）
河北农业大学引进人才科研专项(YJ2023037) （YJ2023037）
