河北中医2026，Vol.48Issue(8)：1263-1267,5.DOI:10.3969/j.issn.1002-2619.2026.08.006
益气健脾法联合快速康复治疗对大肠癌患者术后康复的影响
Effects of nourishing qi to invigorate spleen combined with enhanced recovery after surgery on postoperative rehabilitation in patients with colorectal cancer
摘要
Abstract
Objective To observe the effects of nourishing qi to invigorate spleen combined with enhanced recovery after surgery(ERAS)on postoperative rehabilitation in patients with colorectal cancer.Methods A total of 140 postoperative patients with colorectal cancer and spleen deficiency syndrome were randomly assigned to two groups using a random number table.The control group(n=70)received ERAS after surgery,while the treatment group(n=70)received nourishing qi to invigorate spleen in addition to the same ERAS regimen.Both groups were treated for 21 d.Gastrointestinal function recovery was recorded in both groups.Before and after treatment,traditional Chinese medicine(TCM)syndrome scores,immune function indices(CD3+,CD4+,and CD4+/CD8+),cortisol(Cor),C-reactive protein(CRP),and nutritional status(albumin[ALB],prealbumin[PAB])were compared.Results After treatment,all TCM syndrome scores and the total score decreased in both groups compared with pre-treatment values(P<0.05),and were lower in the treatment group than in the control group(P<0.05).In the treatment group,recovery time of bowel sounds,first flatus time,and first defecation time were shorter than those in the control group(P<0.05).After treatment,the proportions of peripheral blood T lymphocyte subsets CD3+and CD4+,as well as the CD4+/CD8+ratio,increased in both groups compared with pre-treatment values(P<0.05),and were higher in the treatment group than in the control group(P<0.05).After treatment,Cor and CRP levels decreased in both groups compared with pre-treatment values(P<0.05),and were lower in the treatment group than in the control group(P<0.05).After treatment,ALB and PAB levels increased in both groups compared with pre-treatment values(P<0.05),and were higher in the treatment group than in the control group(P<0.05).Conclusion Nourishing qi to invigorate spleen combined with ERAS can alleviate clinical symptoms in postoperative colorectal cancer patients with spleen deficiency syndrome,accelerate gastrointestinal function recovery,improve immune function,reduce stress responses,enhance nutritional status,and thereby promote postoperative rehabilitation.关键词
大肠癌/术后康复/中药疗法/快速康复治疗Key words
Colorectal cancer/Postoperative rehabilitation/Traditional Chinese medicine therapy/Enhanced recovery after surgery分类
医药卫生引用本文复制引用
许成,张育葵,李雪琦..益气健脾法联合快速康复治疗对大肠癌患者术后康复的影响[J].河北中医,2026,48(8):1263-1267,5.基金项目
襄阳市科技计划项目(编号:2022YL40A) （编号:2022YL40A）
