临床神经外科杂志2026，Vol.23Issue(4)：361-366,6.DOI:10.3969/j.issn.1672-7770.2026.04.001
不同海拔地区幕上脑出血患者CT影像学特征对比
Comparison of imaging features of supratentorial intracerebral hemorrhage in patients at different altitudes
摘要
Abstract
Objective To investigate the differences in imaging features of supratentorial spontaneous intracerebral hemorrhage(ICH)between patients at different altitudes and to analyze the influencing factors of CT values.Methods The clinical data of 140 patients with spontaneous supratentorial ICH treated at Taxkorgan Tajik Autonomous County People's Hospital(high-altitude group)and the First Affiliated Hospital of Xinjiang Medical University(low-altitude group)from July 2023 to July 2025 were analyzed retrospectively,including basic information(age,gender,chronic diseases),imaging parameters(hematoma location,hematoma volume,mean hematoma CT value,hematoma shape),and hematological parameters(routine blood tests,coagulation function tests).Results A total of 140 patients were included in this study.Baseline comparisons showed no significant differences between the two groups in age and gender distribution(both P>0.05).Regarding imaging features,the high-altitude group had significantly larger hematoma volumes and significantly higher CT values[(68.8±2.7)HU vs(55.3±7.8)HU,P=0.029]compared to the low-altitude group[(33.4±18.3)mL vs(22.4±15.7)mL,P<0.001].No statistically significant differences were observed between the two groups in hematoma location distribution and hematoma shape(both P>0.05).Correlation analysis revealed a significant positive correlation between CT values and hemoglobin concentration(r=0.542,P<0.001).Multiple linear regression analysis demonstrated that hemoglobin concentration(β=0.489,P<0.001)and altitude(β=0.218,P=0.012)were independent factors influencing CT values,jointly explained 35.6%of the variance in CT values(adjusted R2=0.356,P<0.001).Conclusions The elevated mean hematoma CT values in patients with spontaneous ICH at high altitudes are closely associated with secondary polycythemia.Hypoxic environments influence the imaging manifestations of intracerebral hemorrhage through multiple mechanisms.Clinicians should pay attention to these distinctive imaging features to avoid misdiagnosis.关键词
海拔/脑出血/影像学特征/血红蛋白浓度Key words
altitude/intracerebral hemorrhage/imaging feature/hemoglobin concentration分类
医药卫生引用本文复制引用
努尔艾力江·麦麦提艾力,江荣雷,夏天光,依日扎提·艾力,秦虎,汪永新..不同海拔地区幕上脑出血患者CT影像学特征对比[J].临床神经外科杂志,2026,23(4):361-366,6.基金项目
省部共建中亚高发病成因与防治国家重点实验室高原病项目(SKL-HIDCA-2024-GY4) （SKL-HIDCA-2024-GY4）
