广东石油化工学院学报2026，Vol.36Issue(3)：7-10,4.DOI:10.26962/j.cnki.1991.2026.0043
自由基介导非活化烯烃的氢-二氯甲基化反应
Radical-Mediated Hydrogen Dichloromethylation of Non-Activated Alkenes
摘要
Abstract
This study reports a hydrogen-dichloromethylation reaction of non-activated olefins mediated by radicals in the absence of metal catalysts and synthesizes a series of dichloromethyl substituted alcohol compounds with moderate to high yields.This reaction,using tert-butyl hydroperoxide(TBHP)as radical initiator and hydrogen source and chloroform as dichloromethyl source,has the advantages of wide substrate applicability,mild reaction conditions,and simple experimental operation.It provides an effective way to construct structurally diverse dichloromethyl substituted derivatives under mild conditions.关键词
自由基介导/非活化烯烃/氢-二氯甲基化/叔丁基过氧化氢Key words
radical mediated/non-activated olefins/hydrogen-dichloromethylation/tert-butyl hydroperoxide分类
化学化工引用本文复制引用
蒋延富,黄佳佳,陈桂萍,张建涛,刘卫兵..自由基介导非活化烯烃的氢-二氯甲基化反应[J].广东石油化工学院学报,2026,36(3):7-10,4.基金项目
国家自然科学基金(22401052) （22401052）
广东石油化工学院人才引进项目(2019rc048) （2019rc048）
