日用化学品科学2026，Vol.49Issue(8)：20-25,6.DOI:10.3969/j.issn.1006-7264.2026.08.004
敏感肌适用的微油珠精华液的制备及功效评价
Preparation and efficacy evaluation of a micro-oil bead serum suitable for sensitive skin
齐艳芳 1彭晏 2植洁婷 1章次宏3
作者信息
- 1. 宇肽生物(东莞)有限公司深圳分公司,广东 深圳 518000
- 2. 深圳市维琪科技股份有限公司,广东 深圳 518000
- 3. 宇肽生物(东莞)有限公司,广东 东莞 523000
- 折叠
摘要
Abstract
A firming and anti-wrinkle serum suitable for sensitive skin was prepared by dispersing the oil phase into the aqueous phase under stirring to form uniform micro-oil beads.The effect of viscosity on oil bead size was investigated by examining the relationship between thickener concentration and oil bead diameter in serums with different viscosities.The firming and anti-wrinkle efficacy and safety of the serum were evaluated through human skin fibroblast(HSF)proliferation and cytotoxicity assays.The results showed that when the viscosity ranged from 1 500 to 2 000 mPa·s,the oil bead diameter ranged from 450 to 550 μm,providing an aesthetically pleasing appearance.The serum exhibited no cytotoxicity at concentrations of 2.50%,1.25%,0.625%,0.312 5%,0.156 25%,0.078 125%,0.039 062 5%,and 0.019 531 25%,and significantly promoted the proliferation of HSF cells.These findings indicate that the micro-oil bead serum can be prepared using a simple process and possesses favorable safety,non-irritating properties,and effective firming and anti-wrinkle efficacy.关键词
化妆品/敏感肌/紧致抗皱/细胞实验Key words
cosmetics/sensitive skin/firming and anti-wrinkle/cell assay分类
化学化工引用本文复制引用
齐艳芳,彭晏,植洁婷,章次宏..敏感肌适用的微油珠精华液的制备及功效评价[J].日用化学品科学,2026,49(8):20-25,6.
