新医学2026，Vol.57Issue(8)：910-917,8.DOI:10.12464/j.issn.0253-9802.2025-0389
富血小板血浆及血小板源性外泌体在女性生殖系统疾病中的应用
Application of platelet-rich plasma and platelet-derived exosomes in female reproductive system disorders
摘要
Abstract
Female reproductive system-related diseases,such as intrauterine adhesions,thin endometrium,and premature ovarian insufficiency,have emerged as major clinical problems affecting women's reproductive health.However,conventional treatments are limited by suboptimal efficacy and pronounced adverse effects.Advances in regenerative medicine have introduced novel therapeutic strategies for these conditions.Platelet-rich plasma(PRP),as an autologous biological agent,has demonstrated promising prospects in the treatment of reproductive disorders due to its favorable tissue-repair potential and bio-safety.Recent studies indicate that exosomes are key active components mediating the biological effects of PRP,and they have attracted increasing attention because of their high stability,strong targeting capacity,and low immunogenicity.This review summarizes the biological characteristics of PRP and platelet-derived exosomes,as well as their clinical applications in female reproductive system disorders,with the aim of providing a reference for both clinical practice and scientific research.关键词
富血小板血浆/外泌体/生殖系统/宫腔粘连/薄型子宫内膜/反复种植失败/卵巢功能不全Key words
Platelet-rich plasma/Exosomes/Reproductive system/Intrauterine adhesion/Thin endometrium/Recurrent implantation failure/Ovarian insufficiency分类
医药卫生引用本文复制引用
朱洁茹,欧建平,李小毛..富血小板血浆及血小板源性外泌体在女性生殖系统疾病中的应用[J].新医学,2026,57(8):910-917,8.基金项目
广东省卫生计生适宜技术项目(202303281847292843) （202303281847292843）
