云南化工2026，Vol.53Issue(8)：1-5,5.DOI:10.3969/j.issn.1004-275X.2026.08.01
配体-金属电荷转移促进的电光催化烷烃氧化官能团化研究进展
Electrophotocatalytic Oxidative Functionalization of Alkanes Enabled by Ligand-to-metal Charge Transfer
摘要
Abstract
The direct functionalization of unactivated aliphatic C(sp3)-H bonds under mild conditions continues to pose a formidable chal-lenge,primarily due to their high bond dissociation energies and inherent nonpolar characteristics.This endeavor stands as a pivotal research avenue within the realm of modern synthetic chemistry.The synergistic approach that integrates ligand-to-metal charge transfer(LMCT)-fa-cilitated hydrogen atom transfer(HAT)with electrochemical techniques has opened up a novel pathway for achieving C(sp3)-H bond func-tionalization under such mild conditions.This review offers a comprehensive and systematic overview of the most recent advancements in iron-based and cerium-based catalytic systems,specifically tailored for electrophotocatalytic C(sp3)-H bond functionalization,with a focus on the design principles,catalytic mechanisms and application characteristics of the two systems in reactions including borylation,alkenylation,C-H alkylation of heteroarenes and tandem cyclization,as well as a comparison of the advantages and limitations of different systems.This review aims to clarify the core logic of LMCT-electrophotocatalytic synergistic activation of alkane C(sp3)-H bonds,dissect their reaction mechanisms and application potential,summarize the existing challenges and future development directions,and provide reference for subsequent research in this field.关键词
烷烃/电光催化/配体-金属电荷转移/C(sp3)—H键官能团化/有机电合成/光催化Key words
Alkanes/Electrophotocatalysis/Ligand-to-Metal Charge Transfer/C(sp3)-H Functionalization/Organic Electrosynthesis/Photocatalysis分类
化学化工引用本文复制引用
孙清垚,史吉富,张世伟,雷鑫,侯浩辉,梁德强..配体-金属电荷转移促进的电光催化烷烃氧化官能团化研究进展[J].云南化工,2026,53(8):1-5,5.基金项目
国家自然科学基金(22061024) （22061024）
沪滇科技协同创新项目(26HD0700200,202603AD140004) （26HD0700200,202603AD140004）
云南省基础研究重点计划(202501AS070016). （202501AS070016）
