云南民族大学学报（自然科学版）2026，Vol.35Issue(4)：433-449,17.DOI:10.3969/j.issn.1672-8513.2026.04.001
云木香中倍半萜类成分及其衍生物的结构修饰与药理活性研究进展
Research progress on structural modification and pharmacological activities of sesquiterpenoids and their derivatives in Aucklandia lappa Decne.
摘要
Abstract
Aucklandia lappa Decne.is a traditional Chinese medicine with a long history of use and multiple pharmacological activities.In recent years,with the in-depth research on Asteraceae plants,the chemical constituents and pharmacological effects of Aucklandia lappa have been continuously revealed.This paper systematically reviews the main chemical components of Aucklandia lappa,including dehydrocostus lactone,costunolide,and so on.It further summarizes the research progress on the pharmacological activities of derivatives of these core components after structural modification,particularly the action mechanisms in anti-inflammation,anti-tumor,and gastrointestinal function regulation.It aims to provide a reference for the in-depth research and drug development of Aucklandia lappa and its active components.关键词
云木香/木香烃内酯/抗炎/抗菌/结构修饰Key words
Aucklandia lappa Decne./costunolide/anti-inflammatory/anti-bacterial/structural modification分类
医药卫生引用本文复制引用
杨恒俐,毛泽伟,李艳平..云木香中倍半萜类成分及其衍生物的结构修饰与药理活性研究进展[J].云南民族大学学报（自然科学版）,2026,35(4):433-449,17.基金项目
云南省应用基础研究计划项目中医联合专项(202101AZ070001-326) （202101AZ070001-326）
云南省应用基础研究计划(202201AT070228). （202201AT070228）
