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AHP-CRITIC法结合正交设计优选白术九蒸九制炮制工艺

丁志伟 张兴德 巩梦琳 武漫仪 岳显可

亚太传统医药2026,Vol.22Issue(8):59-65,7.
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亚太传统医药2026,Vol.22Issue(8):59-65,7.DOI:10.11954/ytctyy.202608009

AHP-CRITIC法结合正交设计优选白术九蒸九制炮制工艺

Optimization of the Nine-Steaming and Nine-Processing Technology of Atractylodes Macrocephala by AHP-CRITIC Method Combined with Response Surface Design

丁志伟 1张兴德 2巩梦琳 1武漫仪 1岳显可3

作者信息

  • 1. 云南中医药大学 中药学院,云南 昆明 650500||浙江嘉兴东方国药饮片股份有限公司,浙江 嘉兴 314000
  • 2. 南京中医药大学 药学院,江苏 南京 210023
  • 3. 浙江嘉兴东方国药饮片股份有限公司,浙江 嘉兴 314000
  • 折叠

摘要

Abstract

Objective:To study the optimal processing technology of nine-steaming and nine-processing for Atractylodes macrocephala.Methods:High-Performance Liquid Chromatography(HPLC)was used to determine the contents of Atractylenolide Ⅰ,Atractylenolide Ⅱ,Atractylenolide Ⅲ,and Atractylon in Atractylodes macrocephala processed by nine-steaming and nine-processing.With the contents of these components as evaluation indicators,single-factor experi-ments were conducted to investigate the steaming times,steaming duration,and drying temperature during the steam-ing process of Atractylodes macrocephala;the AHP-entropy weight CRITIC combined weighting method combined with box-behnken response surface was applied to study the nine-steaming and nine-processing technology of Atrac-tylodes macrocephala.Results:The optimized nine-steaming and nine-processing technology for Atractylodes macro-cephala was determined as follows:steaming 4 times,steaming time of 2 hours,and drying temperature of 60℃.Con-clusion:This method is feasible and stable,and can provide a reference for the research on the steaming process of At-ractylodes macrocephala.

关键词

白术/九蒸九制/白术内酯Ⅰ/工艺优化

Key words

Atractylodes macrocephala/nine-steaming and nine-processing/atractylenolide Ⅰ/process optimization

分类

医药卫生

引用本文复制引用

丁志伟,张兴德,巩梦琳,武漫仪,岳显可..AHP-CRITIC法结合正交设计优选白术九蒸九制炮制工艺[J].亚太传统医药,2026,22(8):59-65,7.

基金项目

浙江省科技计划项目(2024C03102) (2024C03102)

亚太传统医药

1673-2197

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