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Hepatitis B virus promotes hepatocellular carcinoma progression by disrupting NSUN2/YBX1-mediated m5C modification of PTEN mRNA

Mengxian Lin Kunqi Chen Hang Li Xinjian Lin Shuxiang Wu Xu Lin

中国病毒学2026，Vol.41Issue(3)：543-560,18.

中国病毒学2026，Vol.41Issue(3)：543-560,18.DOI:10.1016/j.virs.2026.03.001

Hepatitis B virus promotes hepatocellular carcinoma progression by disrupting NSUN2/YBX1-mediated m5C modification of PTEN mRNA

Mengxian Lin ¹Kunqi Chen ¹Hang Li ¹Xinjian Lin ¹Shuxiang Wu ²Xu Lin²

作者信息

1. Key Laboratory of Gastrointestinal Cancer(Fujian Medical University),Ministry of Education,Fuzhou,China
2. Key Laboratory of Gastrointestinal Cancer(Fujian Medical University),Ministry of Education,Fuzhou,China||Fujian Key Laboratory of Tumor Microbiology,Department of Medical Microbiology,Fujian Medical University,Fuzhou,China
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摘要

关键词

Hepatitis B virus(HBV)/Hepatocellular carcinoma(HCC)/RNA 5-methylcytosine(m5C)modifi-cation/Phosphatase and tensin homolog(PTEN)

Key words

Hepatitis B virus(HBV)/Hepatocellular carcinoma(HCC)/RNA 5-methylcytosine(m5C)modifi-cation/Phosphatase and tensin homolog(PTEN)

引用本文复制引用

Mengxian Lin,Kunqi Chen,Hang Li,Xinjian Lin,Shuxiang Wu,Xu Lin..Hepatitis B virus promotes hepatocellular carcinoma progression by disrupting NSUN2/YBX1-mediated m5C modification of PTEN mRNA[J].中国病毒学,2026,41(3):543-560,18.

基金项目

This work was supported by the grants from the National Natural Science Foundation of China(Grant No.U25A20130,82372231 and 82302503)and the Joint Funds for the Innovation of Science and Technology in Fujian Province(2023Y9002 and 2023Y9010). （Grant No.U25A20130,82372231 and 82302503）

中国病毒学

ISSN：1003-5125

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