中国病毒学2026,Vol.41Issue(3):574-585,12.DOI:10.1016/j.virs.2026.05.002
Age-related pharyngeal microbiome and host transcriptomic signatures underlying fever responses in RSV bronchiolitis
Age-related pharyngeal microbiome and host transcriptomic signatures underlying fever responses in RSV bronchiolitis
Ying Li 1Yan Li 2Yamin Sun 3Xiaoxia Lu 4Di Liu 5Yi Yan 4Jingyuan Zhang 4Haizhou Liu 6Muhammad Noman 5Muhammad Arif Rizwan 5Ismaila Damilare Isiaka 5Hebin Chen 4Wenqing Li 4Nan Zhao4
作者信息
- 1. State Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China||University of Chinese Academy of Sciences,Beijing 101409,China||Department of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China
- 2. Department of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Department of Pathogen Biology,School of Basic Medicine,Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China
- 3. National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,Beijing Ditan Hospital,Capital Medical University,Beijing 101409,China
- 4. Department of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China||Pediatric Respiratory Disease Laboratory,Institute of Maternal and Child Health,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China
- 5. State Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China||University of Chinese Academy of Sciences,Beijing 101409,China
- 6. State Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China
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摘要
关键词
Respiratory syncytial virus(RSV)/Bronchiolitis/Age-dependent/Fever/Host response/Airway microbiomeKey words
Respiratory syncytial virus(RSV)/Bronchiolitis/Age-dependent/Fever/Host response/Airway microbiome引用本文复制引用
Ying Li,Yan Li,Yamin Sun,Xiaoxia Lu,Di Liu,Yi Yan,Jingyuan Zhang,Haizhou Liu,Muhammad Noman,Muhammad Arif Rizwan,Ismaila Damilare Isiaka,Hebin Chen,Wenqing Li,Nan Zhao..Age-related pharyngeal microbiome and host transcriptomic signatures underlying fever responses in RSV bronchiolitis[J].中国病毒学,2026,41(3):574-585,12.基金项目
This study was supported by the National Natural Science Foundation of China(32500045,82550120),Natural Science Foundation of Wuhan(2026020301040160),Medical Research Project of Wuhan Health Com-mission(WX23A90),the Natural Science Foundation of Hubei Province(2026AFB683,2021CFA012,2023AFB221),the Funding for Scientific Research Projects from Health Commission of Hubei Province(WJ2021M262),and the Funding for Scientific Research Project from Wuhan Children's Hospital(2024FEBSJJ007,2025FEBSHJJ003). (32500045,82550120)