中国肺癌杂志2026，Vol.29Issue(6)：469-474,6.DOI:10.3779/j.issn.1009-3419.2026.106.17
Ⅳ期肺腺癌伴神经内分泌分化出现PCT异常升高1例并文献复习
Abnormally Elevated Procalcitonin in Stage Ⅳ Lung Adenocarcinoma with Neuroendocrine Differentiation:A Case Report and Literature Review
摘要
Abstract
Procalcitonin(PCT)is a key biomarker widely used in clinical practice for the diagnosis of bacterial infection,assessment of antimicrobial efficacy,and prognostic evaluation.Studies have shown that PCT can also be elevated in various malignancies,correlating closely with tumor progression,metastasis,and poor prognosis.However,the value of PCT in monitoring disease status and treatment response in non-small cell lung cancer(NSCLC)remains unclear.This article reports a case of a patient with previously treated stage IV lung adenocarcinoma with neuroendocrine differentiation,who presented with a marked elevation in serum PCT in the absence of active infection.Following local radiotherapy to the pleural metastatic lesion,the PCT level declined rapidly.This report aims to explore the potential clinical significance of PCT in NSCLC with neuroendocrine differentiation and to provide a reference for disease assessment and prognostic evaluation in patients with similar symptoms.关键词
肺肿瘤/降钙素原/神经内分泌分化/预后/疗效监测Key words
Lung neoplasms/Procalcitonin/Neuroendocrine differentiation/Prognosis/Treatment response monitoring引用本文复制引用
潘勇全,吴婷,蒋金凤,孙天宇,刘晨阳,丁浩..Ⅳ期肺腺癌伴神经内分泌分化出现PCT异常升高1例并文献复习[J].中国肺癌杂志,2026,29(6):469-474,6.基金项目
This paper was supported by the grant from Zhenjiang"Jinshan Talent"High-Level Medical Talents Project(No.JSYC2025009,to Chenyang LIU). 本研究受镇江市"金山英才"医学领域高层次人才项目(No.JSYC2025009)资助 （No.JSYC2025009,to Chenyang LIU）
