中国饲料Issue(15)：45-52,8.DOI:10.15906/j.cnki.cn11-2975/s.2025030070-07
储存时间对茅苍术挥发性成分分析及其抗炎活性的影响
Study on the effects of storage duration on volatile components and anti-inflammatory activity of Atractylodes lancea
摘要
Abstract
The study aimed to investigate the impact of storage duration on the quality of Atractylodes lancea(AL).GC-MS was employed to systematically analyze the dynamic changes in volatile components of AL stored for different periods(0,1year,and 2 years),while LPS-induced RAW 264.7 murine monocyte-macrophage inflammatory models were utilized to evaluate anti-inflammatory activity.The results demonstrated that characteristic volatile components,including atractylodin,hinesol,and β-eudesmol,exhibited the highest initial content during fresh storage(0 year,accounting for 40.71%,19.37%and 6.39%of total volatile components,respectively),with a gradual decline observed over extended storage periods.Cellular experiments revealed no cytotoxicity for volatile components across all storage groups at 50 μg/mL(cell viability>90%),with consistent inhibition of LPS-induced NO release(inhibition rate:29.08%～31.75%).Notably,the 1-year-stored AL displayed a relatively optimal anti-inflammatory trend.This study elucidate the nonlinear correlation between the storage stability of volatile components in AL and their anti-inflammatory efficacy,providing critical experimental evidence for establishing scientific storage standards of traditional Chinese medicinal materials.关键词
茅苍术/挥发性成分/储存时间/GC-MS/抗炎Key words
Atractylodes lancea/volatile components/storage duration/gas chromatography-mass spectrometry/anti-inflammation分类
农业科技引用本文复制引用
钱慧琴,刘姝媛,王迦南,徐海波,冯坤,李彦灵..储存时间对茅苍术挥发性成分分析及其抗炎活性的影响[J].中国饲料,2026,(15):45-52,8.基金项目
河南省高等学校重点科研项目(23B360007) （23B360007）
河南省科技攻关项目(262102310511) （262102310511）
河南省医学教育研究项目(WJLX2025194) （WJLX2025194）
