中国现代医学杂志2026，Vol.36Issue(16)：45-50,6.DOI:10.3969/j.issn.1005-8982.2026.16.007
复张-膨胀比评估急性呼吸窘迫综合征肺可复张性的研究进展
Research progress on the recruitment-to-inflation ratio for assessing lung recruitability in acute respiratory distress syndrome
摘要
Abstract
Acute respiratory distress syndrome(ARDS)is characterized by heterogeneous alveolar collapse and refractory hypoxemia,posing significant challenges to the optimization of mechanical ventilation strategies.Given the substantial inter-patient variability in lung recruitability,optimal approaches for lung recruitment maneuvers(RMs)and positive end-expiratory pressure(PEEP)settings remain controversial.The recruitment-to-inflation ratio(R/I),a recently proposed bedside assessment tool,quantifies alveolar recruitability by analyzing changes in respiratory system compliance across different PEEP levels,thereby providing a basis for individualized ventilation strategies.R/I is simple to perform,requires no additional equipment,and can be repeatedly measured at the bedside to dynamically track treatment responses.Multiple studies have demonstrated good agreement between R/I and recruitability assessed by computed tomography,electrical impedance tomography,and lung ultrasound.However,the current evidence is predominantly derived from small-sample,single-center studies.Measurement discrepancies across different ventilator models may compromise the accuracy of R/I,and no universally accepted threshold for distinguishing high from low recruitability has been established.Future large-scale,multicenter clinical trials are warranted to further validate the reliability of R/I and to clarify its clinical value in balancing the benefits of lung recruitment against the risk of ventilator-induced lung injury in ARDS management.关键词
急性呼吸窘迫综合征/肺复张/复张-膨胀比/机械通气/呼吸力学Key words
acute respiratory distress syndrome/lung recruitment/recruitment-to-inflation ratio/mechanical ventilation/respiratory mechanics分类
医药卫生引用本文复制引用
王一玮,袁伊凡,黑悦,臧奎..复张-膨胀比评估急性呼吸窘迫综合征肺可复张性的研究进展[J].中国现代医学杂志,2026,36(16):45-50,6.基金项目
国家自然科学基金(82301553) （82301553）
